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Vascular Remodeling clinical trials

View clinical trials related to Vascular Remodeling.

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NCT ID: NCT04952883 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Hydrogen Sulfide and Pulmonary Vascular Remodeling on HRCT in Patients With COPD

Start date: December 1, 2016
Phase:
Study type: Observational

HRCT was used to evaluate pulmonary vascular remodeling in COPD. The role of H2S in pulmonary vascular remodeling in COPD was analyzed, in order to provide a basis for seeking new therapeutic targets.

NCT ID: NCT04433429 Completed - Clinical trials for Hypercholesterolemia

Nutraceuticals and Vascular Remodelling

MALTRO
Start date: May 2016
Phase:
Study type: Observational

Aim of the study is to assess the effect of a long-term nutraceutical multitarget approach on lipid profile, inflammatory mediators and vascular remodeling in primary cardiovascular prevention in a setting of controlled dietary habits. The nutraceutical combination used in this study consists of a single pill containing 333 mg of RYR, equivalent to 10 mg of Monacolin K, and 30 mg of Coenzyme Q10 (CoQ10).

NCT ID: NCT04282434 Completed - Clinical trials for Pulmonary Arterial Hypertension

DNA Methylation Dynamics Underlying Arterial Remodeling in PAH Patients: CLEOPAHTRA Clinical Trial

CLEOPAHTRA
Start date: June 14, 2019
Phase:
Study type: Observational

To identify epigenetic-sensitive modifications and novel biomarkers linked to pathogenesis of pulmonary arterial hypertension (PAH), we will perform the first study analyzing differentially-methylated regions (DMRs) in circulating T cells (CD04+ and CD08+) isolated from peripheral blood of patients undergoing right heart catheterization. Moreover, we will perform RNA deep sequencing on lung tissue biopsies to validate if DNA methylation signatures in circulating T cells could reflect perturbations of gene expression in lung tissues.

NCT ID: NCT03356301 Completed - Athletes Clinical Trials

Study of the Aorta Adaptations to Exercise in Triathletes During Sports Season (CoATri)

CoATri
Start date: December 1, 2017
Phase: N/A
Study type: Interventional

Regular sustained physical activity creates a cardiac remodelling : it is athlete's heart. In our preliminary work published in 2016, the investigators demonstrated in a small population of triathletes that there is also a vascular remodelling named athlete's artery. Moreover, the investigators know that left ventricle and aorta behave together like a couple. So they want to study by Cardiovascular Magnetic Resonance Imaging the impact of triathlon on the cardiac AND aortic remodelling.

NCT ID: NCT02721472 Completed - Sickle Cell Disease Clinical Trials

Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease

PADRE
Start date: May 17, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the relationship between plasma DNA levels and micro- and macro-circulatory vascular remodelling in patients with sickle cell disease

NCT ID: NCT02414204 Completed - Clinical trials for Improve Endothelial Function and Decrease Vascular Stenosis

Phosphodiesterase Type 5 Inhibition to Improve Endothelial Function and Vascular Remodeling in Chronic Kidney Disease and End Stage Renal Disease Patients Requiring New Arteriovenous Fistula

Start date: April 2015
Phase: N/A
Study type: Interventional

Patients with stage IV and V chronic kidney disease and end stage renal disease requiring hemodialysis at University of Alabama at Birmingham (UAB) Dialysis Clinics will be recruited from the UAB Vascular Access Clinic, which has been the site for recruitment of patients requiring new vascular access for the last 10 years.