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Factor XIII and Pulmonary Embolism in Neurosurgical Patients

Pulmonary Embolism Clinical Trial

Official title:
Risk Factors for Perioperative Pulmonary Embolism in Neurosurgical Patients in Respect of Factor XIII Activity

Clinical Trial Summary

Two studies (Gerlach et al. 2000; Gerlach et al. 2002) described the impact of factor XIII on the risk of prospective hemorrhage for patients undergoing craniotomy. Since then, factor XIII is measured and substituted in various centers. Few reports support the idea of factor XIII being involved in the formation of deep venous thrombosis and pulmonary embolism. In this prospective observational study, patients undergoing craniotomy for brain tumors or vascular lesions are investigated concerning the incidence of postoperative pulmonary embolism in respect of possible risk factors (factor XIII activity levels, standard coagulation parameters, tumor entity, blood loss).

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01106937
Study type Observational
Source Ludwig-Maximilians - University of Munich
Contact Stefan Grau, Dr.
Phone +4989/7095-0
Email stefan.grau@med.uni-muenchen.de
Status Recruiting
Phase N/A
Start date October 2007
Completion date December 2010
View Details
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