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Vascular Injury clinical trials

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NCT ID: NCT05846321 Recruiting - Vascular Injury Clinical Trials

Registry for Vascular Trauma and Follow-up Examinations

Start date: June 1, 2023
Phase:
Study type: Observational

Within the framework of the project presented here, a registry for traumatic vascular injuries will be established at Augsburg University Hospital. Patients who are treated at our hospital for an isolated vascular trauma or a vascular involvement in (poly-)trauma will be included. This is a rare complication of trauma, so data collection in a registry is useful to pool data on therapeutic procedures and outcome. These patients differ from the usual vascular surgery patient clientele because there is usually no previous vascular disease. Healthy vessels show different physiological responses than pre-diseased vessels. The usual therapeutic procedures and materials are also developed for arteriosclerotic or aneurysmatic vessels. Therefore, a core objective of this study is to assess long-term outcomes after vascular trauma.

NCT ID: NCT05538858 Completed - Clinical trials for Endothelial Dysfunction

Vascular Injury in Mechanical Ventilation: a Proof-of-Concept Study

Start date: December 15, 2022
Phase:
Study type: Observational

Investigation of the effect of mechanical ventilation on biomarkers of microvascular damage

NCT ID: NCT05224635 Enrolling by invitation - Vascular Injury Clinical Trials

The PROspective Observational Vascular Injury Trial (PROOVIT)

Start date: December 30, 2021
Phase:
Study type: Observational

Evidence suggests that the rate of treatable vascular injury is increasing due to improved pre-hospital strategies. The increased rate of vascular trauma occurs in an era of increased sub-specialization, shifting training paradigms and the emergence of endovascular therapies. These factors, in combination with the baseline complexity of vascular trauma, make it particularly important that the management of this injury pattern be evidence-based. However, because all forms and distributions of vascular injury represent only 4% to 9% of trauma admissions, meaningful study of one injury pattern, patient population, therapeutic or surveillance strategy is difficult at a single institution. Further complicating such efforts is the fact that vascular trauma is managed by a wide range of surgical and now endovascular specialists, further fragmenting even a busy trauma institution's experience with vascular injury.

NCT ID: NCT02975518 Completed - Clinical trials for Coronary Artery Disease

Tracking Endothelial Cells in Arterial Injury

Start date: December 2015
Phase: N/A
Study type: Interventional

We plan to track the migratory behaviour of culture-expanded enothelial outgrowth cells in the context of vascular injury sustained during elective coronary angiography. We will use Flouro-deoxyglucose-labelling and PET-CT to track the endothelial cells.

NCT ID: NCT02592655 Completed - Hemorrhage Clinical Trials

A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet

Start date: December 2015
Phase: N/A
Study type: Interventional

This cross-over study of twenty five (anticipated) healthy human subjects will utilize two active control devices, and two different widths of the investigational device. One active control is representative of the usual care tourniquet applied in hospital settings. The second active control is a windlass tourniquet representative of the pre-hospital and military usual care tourniquet device. Two inch and four inch widths of the investigational device will be evaluated. The purpose of this study is to characterize and compare investigational and control tourniquet safety and efficacy. All tourniquets will be applied to the upper thigh. Efficacy data is provided by the presence or absence of popliteal flow when assessed with ultrasound. Mapping of interface pressures between the skin and the tourniquet will provide safety data. A minimum washout of five minutes will be allowed between tourniquet applications. All interventions will be applied in one visit. No follow up visit is anticipated.

NCT ID: NCT00517166 Completed - Vascular Injury Clinical Trials

Survey of Tourniquet Use in a Combat Support Hospital

Start date: August 2006
Phase: N/A
Study type: Observational

Data will be collected on the type of tourniquet and circumstances of its use. Patients with penetrating extremity injury will have clinical and pre-clinical hospital data collected.