Clinical Trials Logo
  1. Home
  2. Vascular Calcification
  3. NCT03314493

Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients

Coronary Artery Calcification Clinical Trial

Official title:
Effect of Spironolactone on the Progression of Coronary Calcification in Peritoneal Dialysis Patients

Clinical Trial Summary

Vascular calcification is a frequent complication in dialysis patients and is strongly associated with mortality. Its pathogenesis is complex and involves a series of markers that act on the vascular microenvironment. There is evidence that aldosterone is one of the biomarkers and may have a role in osteoinductive pathways.The aim of this study was to evaluate the effect of spironolactone, an inhibitor of mineralocorticoid receptor, in the progression of coronary calcification in patients undergoing peritoneal dialysis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03314493
Study type Interventional
Source Professor Fernando Figueira Integral Medicine Institute
Contact
Status Completed
Phase Phase 3
Start date November 7, 2014
Completion date November 10, 2016
View Details
See also
  Status Clinical Trial Phase
Unknown status NCT02498457 - The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Patients N/A
Completed NCT00379899 - ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis Phase 4
Recruiting NCT05346068 - The Value of IVL Compared To OPN Non-Compliant Balloons for Treatment of RefractorY Coronary Lesions (VICTORY) Trial N/A
Completed NCT02966028 - Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD) Phase 2
Completed NCT01992848 - MAP-Calcification: MicroRNAs as Potential Biomarkers for Coronary Artery Calcification N/A
Recruiting NCT06181240 - Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE) N/A
Terminated NCT05508893 - Screening for Coronary Artery Disease USing Primary Evaluation With Coronary CTA in Aviation Medicine (SUSPECT) N/A
Recruiting NCT06075602 - COMPLEX Registry - A Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting With compLEX and Calcified Coronary Artery Disease
Completed NCT05112250 - IVL for Stent Underexpantsion
Recruiting NCT06379295 - Coronary Artery Calcification Assessed on PET Scanner (PET : Positron Emission Tomography)
Completed NCT02913144 - 7 Year Follow-up Study of the DanRisk Population N/A
Completed NCT00860847 - Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH) Phase 3
Not yet recruiting NCT04319666 - Intravascular Balloon Lithotripsy in Left Main Stem Percutaneous Coronary Intervention N/A
Completed NCT03967366 - Melatonin and Coronary Artery Calcification
Recruiting NCT05818098 - Coronary Intravascular Lithotripsy System in Patients With Coronary Artery Calcification (VIGOUR) N/A
Recruiting NCT05283538 - Comparison of Cardiovascular Risk Stratification in Young People With Type 1 Diabetes by Coronary Calcium Score to ESC/ESA2019 Recommendations N/A
Recruiting NCT05451368 - Neointimal Features in Patients With Restenosis of Calcified Lesions
Recruiting NCT04742478 - ROVUS Asia Registry (Evaluate Safety and Effectiveness of Rotational Atherectomy and Intravascular Ultrasound for Heavily Calcified Coronary Lesion)
Recruiting NCT05259046 - The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health N/A
Recruiting NCT01101698 - Vitamin K2 and Vessel Calcification in Chronic Kidney Disease Patients Phase 4