Varicose Vein Clinical Trial
Official title:
Effect of Intensive Sports Practice on Lower Limb Varicose Veins
Compare the frequency of varicose veins in the lower limbs in a population exposed to intensive sport compared to individuals matched by sex, age and body mass index (BMI) did not have an intensive sport.
Chronic venous disease is a very common disease in industrialized countries. The prevalence
of this disease is estimated in France 30.1% in men and 50.5% women.
Sufferers report pain, heaviness and itching of the lower limbs, and these symptoms are
increased at night and in a warm environment. Clinically chronic venous disease resulting in
varicose veins (veins visible under the skin, tortuous and dilated), edema (swelling
predominant at the ankles) and in the later stages include skin damage of up 'to the ulcer.
The pathological mechanisms underlying chronic venous disease are mainly related to
incontinence of the valves of the veins of the lower limbs. The initial role of these valves
is to allow the return of blood to the heart and prevent it falls constantly in the legs. A
breach of these valves therefore will result in an alteration of venous return and dilatation
of the affected veins. It will be highlighted by a venous reflux when analyzing Doppler.
A number of parameters have been identified as factors favoring chronic venous disease in the
lower limbs. Thus heredity (family history of venous disease), age, number of pregnancies
among women, a history of phlebitis, overweight and physical inactivity increase the risk of
chronic venous disease.
The effects of physical activity:
The practice of physical activity helps fight against physical inactivity. It is recognized
as a protective factor against chronic venous disease. That is why the French and
international companies of medicine and vascular surgery have incorporated in their
recommendations to patients the practice of moderate physical activity and regular part of
the prevention and treatment of chronic venous disease.
Moreover, the impact of intensive practice of a sport (versus "moderate and regular physical
activity") of chronic venous disease is not known. Assumptions were issued from the
nineteenth century on the possible risk of fostering the emergence of chronic venous disease
at an excessive sports. Thus, from the 1820s Dr. Rima Thomas, surgeon of Napoleon's army,
stated: "inertia as much as excessive activity come together to produce the same effect, the
varicose vein." This idea is still relevant, in fact some experts recommend, at this time,
intensive sports wear compression devices in the lower limbs during sports practice to
prevent this phenomenon. However, no study has established a link between intensive practice
of sport and venous condition of the legs.
The purpose of the study:
VARISPORT The study will aim to analyze the condition of the veins of the lower limbs in two
groups of voluntary individuals, aged 18 to 80 years, in the same population:
- An "intensive sport practice": This group will consist of men and women who practice for
more than 6 months, a drive of at least 8 hours / week, intense, above the ventilatory
threshold, or 60-70 % maximum oxygen consumption or 70- 80% of maximum heart rate, ie
beyond a moderate slowdown. If stopping the intensive sport practice, the duration of
the stop at the time of the study should be less practice time.
- A "control" group: the subjects included in this group will have profiles that
approximate subjects of the group "intensive practice sports", same sex, same age, BMI
close; but the practice of a sport is less than 8 hours per week.
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