Epidemiology of Abnormal Vaginal Discharge During Pregnancy

Status Recruiting

Clinical Trial Summary

Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the flora. There are many types of infections that affect the vagina, the most common three types of infection: bacterial vaginosis, trichomoniasis, and candidiasis. Bacterial vaginosis is the most common vaginal infection in women of reproductive age causing thin and milky vaginal discharge with a fishy odor. Trichomoniasis causes a frothy, greenish-yellow discharge with a foul smell. Vaginal Candidiasis is one of the most common fungal infections of the female genital tract and the second most common vaginal infection affecting women of reproductive age (after the bacterial infection worldwide. It affects more than 75% of women at least once in their lifetime, with approximately 50% of them also suffering a single recurrence. About 75% of patients suffering from candidiasis are asymptomatic, but it may be symptomatic with clinical picture characterized by itching, vaginal pain, vulvar burning sensation, dyspareunia, dysuria and mildly unpleasant odor, erythema and vulvar edema, white-yellowish plaques on the walls of the vagina and cervix and cheesy vaginal discharge. The risk of vulvo-vaginal candidiasis increases by 30% during pregnancy also in pregnancy, the presence of vaginitis is related to abortion, intrauterine infection, fetal growth retardation, premature rupture of membranes, preterm birth, low birth weight, puerperal infection, and other adverse pregnancy outcomes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04719754
Study type	Observational
Source	Assiut University
Contact	Doaa Makarem, MSc
Phone	+201065312287
Email	Doaamakarem5@gmail.com
Status	Recruiting
Phase
Start date	June 1, 2021
Completion date	December 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00324246` - Feasibility Study of the NEW NORMA-SENSE	Phase 3
Recruiting	`NCT05021315` - Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection	Phase 3
Not yet recruiting	`NCT05997160` - Research on Vaginal Microbiota Evaluation Unified Standards Based on Gram Staining
Recruiting	`NCT05557318` - Using Micro Electro Mechanical Systems to Detect the Air of Vaginal Discharge	N/A
Completed	`NCT05044156` - Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women
Completed	`NCT00694928` - Vaginal Infection Study 2	Phase 3
Not yet recruiting	`NCT05590195` - Effect of PreforPro® on Urinary and Vaginal Health	Phase 3
Completed	`NCT03898726` - Laparoscopic Versus Transvaginal Cuff Closure	N/A
Withdrawn	`NCT01542606` - Performance Proof of Product Developed to Detect Abnormal Vaginal pH	N/A
Not yet recruiting	`NCT05806879` - Impact of Maternity Napkins on the Incidence of Vaginal Infections in the Post-partum Period	N/A
Completed	`NCT02308046` - Multi-Center Study of New Medications to Treat Vaginal Infections	Phase 3
Completed	`NCT02308007` - Multi-Center Study of New Medications to Treat Vaginal Infections	Phase 3
Completed	`NCT02308033` - Multi-Center Study of New Medications to Treat Vaginal Infections	Phase 3
Completed	`NCT01599416` - Influence of U-relax on Vaginal Health Promotion and HPV DNA Test Change From Positive to Negative	N/A
Completed	`NCT03008421` - Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy	N/A
Completed	`NCT03261804` - Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users
Terminated	`NCT05788991` - Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis	Phase 4
Completed	`NCT01843166` - Vaginal Estrogen With Pessary Treatment	N/A
Not yet recruiting	`NCT03532464` - Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection	Phase 4
Completed	`NCT01055106` - Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis	Phase 2