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Clinical Trial Summary

Labor induction is a common medical technique. There is no consensus on which technique is better than the others. Misoprostol is an analogue of Prostaglandin E1 previously used off-label in labor induction. Its low cost, room-temperature storage, and diverse route options have made it an alternative to PGE2 in labor induction. As of 2018, oral misoprostol 25 μg tablet was licensed for labor induction. Very few studies have been performed on oral misoprostol 25 μg and none compared it with the PGE2s mostly used in induction on unfavorable cervix at term. The investigators compared the safety and the efficacy between the oral misoprostol 25 μg Angusta® used since 20/02/2020 and the vaginal dinoprostone previously used in gel or diffuser over two consecutive periods from 01/01/2019 to 19/02/2020 for the dinoprostone and from 20/02/2020 to 07/04/2021 for the misoprostol.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04955847
Study type Observational
Source Centre Hospitalier Universitaire, Amiens
Contact Fabrice Sergent, Pr
Phone 03 22 08 74 00.
Email sergent.fabrice@chu-amiens.fr
Status Recruiting
Phase
Start date July 5, 2021
Completion date December 2023

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