Clinical Trial Details
— Status: Recruiting
Administrative data
NCT number |
NCT05537714 |
Other study ID # |
22-0682 |
Secondary ID |
|
Status |
Recruiting |
Phase |
|
First received |
|
Last updated |
|
Start date |
August 6, 2023 |
Est. completion date |
August 31, 2024 |
Study information
Verified date |
September 2023 |
Source |
East Carolina University |
Contact |
Alice Richman, PhD |
Phone |
2523471959 |
Email |
richmana[@]ecu.edu |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
In the proposed study, the investigators will conduct qualitative interviews and focus groups
with Black, Hispanic, and medically underserved communities, living in the rural south and
will provide a quantitative survey (mixed methods) to identify reasons for vaccine hesitancy,
including any structural barriers experienced by this population. The investigators will
assess what vaccination messaging was received by trusted individuals and how this messaging
may have impacted vaccination behavior. This mixed methods study design will allow for a
comprehensive picture of vaccine equity and hesitancy for this population. The quantitative
survey provides a focused and concrete uncovering of the issues and relationships and the
qualitative design allows for a detailed, contextualized insight into lived experiences.
Coupled together, this mixed methods design will provide a rich depiction of the underlying
drivers of vaccine hesitancy, structural barriers to vaccination, and messaging that impacted
uptake for medically underserved and rural populations.
Description:
Objective 1: To identify reasons for vaccine hesitancy, structural barriers to vaccination,
vaccine messaging received, and vaccination behavior among medically underserved and
vulnerable populations living in the rural south.
Objective 2: To assess vaccine messaging from trusted individuals (e.g., clergy/church
leaders, community health workers, and community leaders) who serve medically underserved and
vulnerable populations living in the rural south.
Objective 3: To identify best vaccine confidence and uptake strategies to improve vaccine
acceptance, confidence, and trust among medically underserved and vulnerable populations
living in the rural south.
Hypotheses:
H1a. It is hypothesized that top reasons for vaccine hesitancy may include access to care
issues (such as transportation, long wait times, no available appointments, not sure where to
go, no internet, and language barriers), safety and efficacy concerns, distrust in government
and health organizations, as well as lack of information and/or misinformation.
H1b. It is hypothesized that structural barriers to vaccination may include geographic
barriers, access to information, clinic/outlet location or trusted points of access, internet
access, immigrant status, language, transportation, among others.
H1c. It is hypothesized that vaccine messaging received from trusted individuals in the
communities (i.e., faith-based leaders, community health workers, and community leaders) will
have impacted confidence and uptake more so than other vaccine messaging efforts.
H2. It is hypothesized that the vaccine messaging from trusted individuals will be mixed with
some messaging based on science and some based on anecdotal evidence. It is not well-known
what messages are being delivered around vaccination from trusted individuals who serve our
priority population and thus, we can only hypothesize that the messaging will vary.
H3. It is hypothesized that the most effective strategies to boost vaccine confidence and
uptake for vaccine hesitant, medically underserved, and vulnerable populations living in the
rural south will include culturally tailored messaging from engagement with trusted
individuals.