Testing Messages to Promote HPV Vaccination

Vaccine Hesitancy Clinical Trial

Official title:

TESTING MESSAGES TO PROMOTE USE OF AN HPV ONLINE INTERVENTION

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05206669
• Other study ID #: 16-0447
• Status: Completed
• Phase: N/A
• Start date: November 18, 2016
• Est. completion date: March 5, 2017

Study information

• Verified date: January 2022
• Source: University of Colorado, Denver
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Hispanic women have the highest rates of HPV-related cervical cancer compared to all other groups in the U.S. Previous research has delineated several unique barriers to HPV vaccination among Hispanic women, suggesting that interventions that focus on addressing these barriers may improve HPV vaccination compliance in this population. To address some of these unique barriers, an online tailored messaging intervention was developed and tested. Initial analyses demonstrate that participants exposed to an online intervention demonstrated higher intentions to vaccinate for HPV after viewing the informational materials. The next phase of the project will be comprised of promoting use of the online intervention to the general public through the use of theory-based, pretested messages delivered via advertisements on Facebook and Twitter. Specifically, messages will be targeted based on differences between Hispanic parents of adolescents and Hispanic young adults. Previous research has explored the use of the Extended Parallel Processing Model as a theory to guide messages designed to promote health behaviors. The current study extends this work in the area of HPV prevention. Specifically, it seeks to examine the use of this theory as a means to stimulate information seeking behavior in the form of use of the previously developed online intervention that provides information about HPV. We also hope to make a significant contribution to research demonstrating the importance of targeting messages based on differences in population characteristics. Additionally, this study seeks to build on research examining the use of social media sites as a means for implementing health interventions and promoting positive health outcomes. Ultimately, the current study seeks to improve both the HPV vaccination decision-making process and HPV vaccination rates. If this was achieved among the Hispanic population it could substantially decrease disparities in cervical cancer and other HPV-related diseases.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 784
• Est. completion date: March 5, 2017
• Est. primary completion date: March 5, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• For parents eligibility criteria were being: 1) of Hispanic or Latino origin, 2) 18 years or older, 3) a parent or guardian of a child ages 11-17 who had not been vaccinated for HPV.
• For young adults eligibility were being: 1) of Hispanic or Latino origin, 2) 18-26 years of age (vaccine eligibility at the time of data collection, and 3) having not been vaccinated for HPV.

Exclusion Criteria:

• Being under 18 years of age
• Not identifying as Hispanic or Latino
• For parents, having no children ages 11-17 or having only children already vaccinated for HPV
• For young adults, having already been vaccinated for HPV or no longer being eligible due to age (>26)

Related Conditions & MeSH terms

• Intention
• Vaccine Hesitancy

Intervention

Behavioral:
• Health Messages
Brief messages providing information about the effectiveness of HPV vaccines. Messages included embedded links where participants could find more information.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Colorado, Denver

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Intention to Seek Information - 1	Hyperlinks were embedded in intervention messages where participants were told they could find more information about HPV. A click on the link was considered intention to seek information. Not clicking on the link was considered no intention to seek information.	1 day (one time while participants viewed the brief intervention.)
Primary	Intention to Seek Information - 2	Intention to Seek Information survey items measure participants likelihood to seek information about HPV. Survey items included a Yes-No response to the statement "I intend to look for more information about the HPV vaccination within the next 30 days." Those who answer "Yes" were then shown a series of questions prompting them to indicate their likelihood of seeking more information about the HPV vaccination from their "doctor or healthcare provider," "a friend of family member," "the Internet," and "other sources." Responses were measured on a 7-point Likert-type scale that ranged from Very Likely to Very Unlikely. Those who answered "No" were shown the question "Which of the following best represents your reason for not seeking information about the HPV vaccine?". Responses included 1) low interest in the topic, 2) already well informed on the topic, 3) topic is not relevant to me, and 4) information on this topic is upsetting to me.	Outcome was measured one time immediately post-intervention via the post-survey items described to assess their degree of intention.
Secondary	Intention to Vaccinate for HPV	Intention to Vaccinate for HPV measures participants willingness to vaccinate for HPV. It was measured using a single item stating "I intend to get vaccinated against HPV within the next 6 months." Reponses were measured on a 7-point scale ranging from "Strongly agree" to "Strongly disagree."	Outcome was measured one time immediately post-intervention via the post-survey items described to assess their degree of intention