Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Kidney Transplant Recipients -ChronoVAX — CHRONOVAX  

Vaccination; Infection Clinical Trial

Official title: Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Kidney Transplant Recipients -ChronoVAX

Status Recruiting

Clinical Trial Summary

Immune response to influenza vaccine in kidney transplant patients

Clinical Trial Description

Seasonal influenza vaccination is recommended for kidney transplant patients, as influenza is responsible for significant morbidity and mortality in this immunocompromised population. Nevertheless, injection of influenza vaccine induces a protective immune response in only 20% to 40% of patients. Today, there are no recommendations regarding the injection time of influenza vaccine in the general population or in immunocompromised patients. In this context, recent studies conducted in healthy subjects have shown that the time of vaccination can have an impact on vaccine efficacy. This is the case for BCG, influenza, COVID-19. On this basis, we formulate the main hypothesis that the administration of influenza vaccine to kidney transplant patients would be more effective when carried out in the morning than in the evening. ;

Related Conditions & MeSH terms

• Influenza, Human
• Vaccination; Infection

• NCT number: NCT06088563
• Study type: Interventional
• Source: Centre Hospitalier Universitaire de Nice
• Contact: GOSSET Clément, MD
• Phone: 492038632
• Email: gosset.c@chu-nice.fr
• Status: Recruiting
• Phase: N/A
• Start date: October 26, 2023
• Completion date: October 26, 2024