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Uterine Leiomyoma clinical trials

View clinical trials related to Uterine Leiomyoma.

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NCT ID: NCT06115408 Recruiting - Uterine Leiomyoma Clinical Trials

Evaluation of Using Dienogest and N-Acetyl Cysteine on the Volume of Uterine Leiomyoma

Start date: July 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

This 2 arm randomized clinical trial will assess the impact of Dienogest and N-Acetyl Cysteine on volume reduction of uterine leiomyoma

NCT ID: NCT04874246 Completed - Uterine Leiomyoma Clinical Trials

Comparison of Concentration of Vasopressin During Robot-assisted Laparoscopic Myomectomy

VALENTINE
Start date: May 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of the concentration of vasopressin, which is used as a method for reducing blood loss in robot-assisted laparoscopic myomectomy.

NCT ID: NCT04819633 Completed - Uterine Leiomyoma Clinical Trials

Evaluating Serum Sestrin in Leiomyoma Patients

Start date: January 1, 2021
Phase:
Study type: Observational

Leiomyomas are the most common benign neoplasms of women's reproductive system affecting 20-30% of women within the reproductive ages. Sestrins are serum proteins which are highly expressed under circumstances of DNA damage, hypoxia and oxditive stress and play an important role in autophagia. The aim of this study is to evaluate the relationship of serum sestrin proteins with development of leiomyomas.

NCT ID: NCT04519593 Recruiting - Clinical trials for Postoperative Complications

ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma

Start date: September 27, 2020
Phase: N/A
Study type: Interventional

A phase 3 multicenter unblinded randomized controlled trial comparing the temporary uterine blood supply occlusion with conventional approach during laparoscopic myomectomy in patients with uterine leiomyoma.

NCT ID: NCT04282863 Not yet recruiting - Clinical trials for Surgical Procedure, Unspecified

Comparison Between Robotic (RM) and Laparoscopic Myomectomy (LM)

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This is a single-blinded RCT evaluating the effect of robotic-assisted (RM) or conventional laparoscopic surgery (LM) in the management of uterine leiomyomas.

NCT ID: NCT03847077 Completed - Uterine Leiomyoma Clinical Trials

Trial of a Patient Education Tool For Leiomyoma

PETAL
Start date: October 21, 2015
Phase: N/A
Study type: Interventional

The goal of this study was to assess whether using a multimedia tool would enhance patient education and counseling on uterine leiomyomata.

NCT ID: NCT03751124 Completed - Uterine Fibroids Clinical Trials

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Start date: October 16, 2018
Phase: Phase 3
Study type: Interventional

The objectives of this randomized withdrawal study are to evaluate the long-term efficacy and safety of the combination of relugolix, estradiol (E2) and norethindrone acetate (NETA), once daily, for up to 104 weeks in patients with uterine fibroids who have completed a total of 52 weeks of treatment, including a 24-week treatment period in a parent study (study MVT-601-3001 or MVT-601-3002) and a 28-week treatment period in the open-label extension study (MVT-601-3003), and who meet the definition of responder, defined as a patient who demonstrates a menstrual blood loss of < 80 mL and at least a 50% reduction from parent study baseline menstrual blood loss volume on the alkaline hematin analysis of the feminine products returned at Week 48 in the extension study.

NCT ID: NCT03535610 Completed - Uterine Leiomyoma Clinical Trials

Uterine Artery Embolization With Microspheres in Patients With Leiomyoma.

EMBOSOFT I
Start date: August 13, 2018
Phase: N/A
Study type: Interventional

To evaluate the therapeutic response to uterine artery embolization in 30 patients with leiomyoma using the microspheres Embosoft (Embosoft® - Scitech Medical).

NCT ID: NCT03328260 Completed - Uterine Leiomyoma Clinical Trials

High Intensity Focused Ultrasound in Uterine Myoma

Start date: December 12, 2017
Phase: N/A
Study type: Interventional

Aim to evaluate the efficacy of safety of newly developed, high intensity focused ultrasound device in women with symptomatic uterine leiomyoma

NCT ID: NCT03219385 Not yet recruiting - Uterine Leiomyoma Clinical Trials

Directed Ablation of Uterine Fibroids Using a Noninvasive Approach

DIANA
Start date: September 2018
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the safety and effectiveness of the Mirabilis System for treating uterine fibroids in women who are seeking relief from fibroid-related abnormal uterine bleeding but want to avoid hysterectomies or other surgical procedures. The Mirabilis System is an investigational device that delivers high-intensity focused ultrasound (HIFU) to the uterus using integrated ultrasound imaging guidance to offer noninvasive treatment for uterine fibroids. With the Mirabilis System, HIFU is applied noninvasively through the skin using an applicator that is placed against the abdomen. No incisions or surgical procedures are required. During this study, eligible patients will have one or more fibroids treated with the Mirabilis System and will then remain in the study for a total of 36 months after treatment to monitor the occurrence of adverse events. Primary endpoints will be assessed at 12 months after treatment, while secondary endpoints will be assessed at variable times ranging from immediately after treatment up to 36 months after treatment.