Uterine Fibroids Clinical Trial
Official title:
Magnetic Resonance Elastography (MRE) of Uterine Fibroids
The purpose of this study is to gain additional information regarding use of Magnetic
Resonance Elastography (MRE) for uterine fibroid characterization. In this study, the
investigators will use a new noninvasive technology, MRE, to further characterize the
elastic properties of the uterine fibroids. To date, very little is known concerning how the
tissue composition of the uterine fibroid may affect its treatment with Magnetic Resonance
Guided Focused Ultrasound (MRgFUS).
In this study, the investigators will use a new noninvasive technology, magnetic resonance
elastography (MRE), to further characterize the elastic properties of the uterine fibroids.
This information will be gathered during routine magnetic resonance imaging for symptomatic
uterine fibroids. It is known that some fibroids with increased T2-signal on Magnetic
Resonance Imaging(MRI) can be more difficult to treat.
This information will be gathered during routine magnetic resonance imaging for symptomatic
uterine fibroids.
This is a single-site, non-randomized pilot study to determine whether Magnetic Resonance
Elastography (MRE) can be optimized for clinical use as part of the patients routine
clinical imaging and to correlate with MR signal characteristics of the uterine fibroid.
MRE is performed at the end of the examination after the standard Magnetic Resonance Imaging
protocol.
Aims:
Specific Aim 1: To acquire magnetic resonance elastography images on women who have a
clinically ordered pelvic magnetic resonance imaging (MRI) for uterine fibroids.
Specific Aim 2: To examine the correlation between MRE stiffness values and MR T2 signal
characteristics for uterine fibroids. For a subset of patients going on to surgery
correlation with pathology can also be performed.
This study will seek to determine whether MRE can be performed in the pelvis on a routine
clinical basis as well as correlating the MRE findings with magnetic resonance signal
characteristics. There are no additional risks to the patient and no additional cost to the
MRI exam.
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Observational Model: Cohort, Time Perspective: Prospective
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