Clinical Trials Logo

Uterine Fibroids clinical trials

View clinical trials related to Uterine Fibroids.

Filter by:

NCT ID: NCT00737282 Terminated - Uterine Fibroids Clinical Trials

Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine Fibroids

Start date: October 2008
Phase: Phase 3
Study type: Interventional

The safety of Proellex 25 and 50 mg administered once daily for three treatment cycles (four months each) will be evaluated.

NCT ID: NCT00735553 Terminated - Uterine Fibroids Clinical Trials

Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids

Start date: August 2008
Phase: Phase 3
Study type: Interventional

Premenopausal women with symptomatic uterine fibroids will be randomized to either Proellex 25mg or 50mg or placebo for one treatment cycle (four months). Safety and effectiveness between 50 mg versus placebo, and between 25mg and placebo will be analyzed.

NCT ID: NCT00702702 Terminated - Anemia Clinical Trials

Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids

Start date: June 2008
Phase: Phase 3
Study type: Interventional

Eligible female subjects will be randomly assigned to one of the three treatment groups. Subjects will receive 325 mg (65 mg elemental iron) iron supplements to be taken twice daily during study drug treatment. The study duration is approximately six months, which is comprised of a 4 - 6 week screening period, a three-month drug treatment period, and a one-month follow-up period.

NCT ID: NCT00683917 Terminated - Uterine Fibroids Clinical Trials

Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids

Start date: May 2008
Phase: Phase 2
Study type: Interventional

PK of 25 mg and 50 mg Proellex® administered once daily (QD) over a 4-month period.

NCT ID: NCT00584207 Terminated - Uterine Fibroids Clinical Trials

Radiofrequency Ablation of Uterine Fibroids

Start date: March 2004
Phase: Phase 0
Study type: Interventional

This research study is being conducted to evaluate the safety and effectiveness of ablation (destruction) of uterine leiomyomas (fibroids) using electrocautery heating guided by ultrasound. We are doing this to look for a less invasive method of treatment for patients with uterine fibroids. One method that is being used in other areas of the body to treat masses is radiofrequency electrocautery. This method may be performed for the treatment of uterine fibroids by placing a small diameter needle through the wall of the vagina into the fibroid guided by an ultrasound probe. An optional approach is to place the needle through the skin of the abdomen into the fibroid guided by an ultrasound probe. Once the needle is in the fibroid, the electrocautery current is applied and the fibroid is destroyed by heating. This would be done before hysterectomy (removal of the uterus). We are trying to test to see if this type of treatment can be applied to uterine fibroids. We are trying to develop radiofrequency electrocautery as one of the methods to treat fibroids without surgery.

NCT ID: NCT00496080 Terminated - Uterine Fibroids Clinical Trials

Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related Bleeding

DUAO
Start date: June 2007
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of Doppler guided uterine artery occlusion (D-UAO) for the reduction of fibroid associated bleeding.

NCT ID: NCT00496067 Terminated - Uterine Fibroids Clinical Trials

Uterine Artery Occlusion for Fibroid Related Bleeding

Start date: April 2007
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.

NCT ID: NCT00232713 Terminated - Pregnancy Clinical Trials

Uterine Fibroid Pregnancy Registry

Start date: December 2005
Phase:
Study type: Observational

The Uterine Fibroid Pregnancy Registry is a USA and European-based registry designed to monitor pregnancies in women with uterine fibroids in order to 1. estimate the risk ratio of birth defects in women with uterine fibroids who were treated or untreated during pregnancy and 2. detect any pattern of birth defects among pregnancies in specific treatment groups. Those pregnant women exposed to various therapies used to treat uterine fibroids will be compared with those not exposed to treatment in order to detect any potential increase in the risk of major birth defects.