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Usability clinical trials

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NCT ID: NCT06046053 Recruiting - Safety Clinical Trials

MATRIX-002: Trial to Assess Acceptability and Safety of Two Placebo Vaginal Films

Start date: October 18, 2023
Phase: Early Phase 1
Study type: Interventional

This study will enroll approximately 100 HIV-negative persons, aged18-45 years, and assigned female sex at birth from sites in the United States, Kenya, South Africa, and Zimbabwe. The study will assess the acceptability and safety of two placebo vaginal films. The placebo films do not contain any active medication, are the same size, but differ by shape (square versus rounded corners). Participants will be randomly assigned to one of the two films and asked to use (self-insert) the assigned film two times (approximately one month apart). Participants will be asked to refrain from sexual activity during the first month of use and may resume usual sexual activity during the second month of use. The study involves answering questions, undergoing pelvic examinations, and collecting blood and vaginal fluid samples. The study involves a total of 10 visits/contacts, including in person visits and telephone calls over approximately 9 weeks. In addition, both participants and approximately 30 of their sexual partners will be asked to take part in in depth interviews to further assess acceptability, attitudes, and experiences with film use to gauge interest in the future use of vaginal films as a HIV prevention option.

NCT ID: NCT05937646 Recruiting - Critical Care Clinical Trials

Improving Providers' Decision-Making and Reducing Information Overload Using Information Visualization in EHRs

Start date: July 24, 2023
Phase: N/A
Study type: Interventional

This study aims to test the efficacy of an information visualization dashboard on decision-making using a randomized controlled trial with crossover. This study aims to test the efficacy of using an information visualization dashboard on ICU providers' decision-making, efficiency, and performance compared to their institutional EHR through a randomized control trial with crossover.

NCT ID: NCT05608967 Recruiting - Prehabilitation Clinical Trials

Effect of a Prehabilitation Mobile Application Versus Standard of Care Before Colon Cancer Surgery.

PREHAPP
Start date: September 1, 2021
Phase:
Study type: Observational [Patient Registry]

Pilot study to evaluate the effect of prehabilitation programme through a mobile application PREHapp in colon cancer surgery. The objectives of this pilot study were to evaluate the usability of the PREHapp for people undergoing colon cancer surgery, estimate the effect of the app on functional recovery after surgery and to evaluate complications during the postoperative period after 4 weeks of follow-up.

NCT ID: NCT05499572 Recruiting - Usability Clinical Trials

Usability of Levodopa Cyclops™ vs INBRIJA® in Parkinson's Patients

DPI-6
Start date: February 29, 2024
Phase:
Study type: Observational

Currently there is one Levodopa inhaler on the market, the INBRIJA® inhaler. When looking at the user instructions for the INBRIJA®, multiple steps are necessary including preparing and cleaning the inhaler. The Levodopa Cyclops™ inhaler also requires steps to be ready-for-use, however there are less steps required to reach this 'ready-for-use' state. This is mainly because the medicine (Levodopa) is already prefilled in the inhaler. Moreover, the Levodopa Cyclops™ is a single-use inhaler and cleaning steps are not necessary. Since both inhalers should be used during off episodes, there might be a preference for one inhaler over the other due to the instructions. An off episode might impair the ability and length to successfully operate an inhaler due to mental or mobility issues. This study investigates if Parkinson patients have a preference for one of the inhalers based on handling steps, ease-of-use, understandability.