Antegrade Double-J Stent Placement for the Treatment of Malignant Obstructive Uropathy

Urologic Neoplasms Clinical Trial

Official title:

Antegrade Double-J Stent Placement for the Treatment of Malignant Obstructive Uropathy: a Single Center Experience

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04649970
• Other study ID #: U23459
• Status: Completed
• Start date: January 1, 2013
• Est. completion date: February 2, 2020

Study information

• Verified date: December 2020
• Source: Université de Sousse
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Ureteral double- J stent is usually inserted by retrograde approach for the treatment of obstructed upper urinary tract. The antegrade approach, can a suitable alternative in certain situations without the need for general or spinal anesthesia. The present study demonstrates the indications, success rate, and complications of this approach in the treatment of malignant obstructive uropathy.

Description:

Data of consecutive patients in whom antegrade ureteral stent¬ing was performed between January 2013 and February 2020 were retrospectively analysed using patient records and radiology reports. A total of 174 patients (sexe ratio = 0.51, age range 9-91 years; mean age, 54 years) were included in the study.

Ureteral obstruction was caused by bladder cancer (n=92), uterin cancer (n=31), prostate cancer (n=28), colorectal cancer (n= 15) and retroperitoneal tumor (n= 8) (Table 1).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 174
• Est. completion date: February 2, 2020
• Est. primary completion date: June 29, 2017
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• malignant uropathy obstruction

Exclusion Criteria:

• benign uropathy obstruction

Related Conditions & MeSH terms

• Urologic Neoplasms

Intervention

Procedure:
• Antegrade double-J stent
After exchanging the nephrostomy catheter over the J-tipped guidewire, 5 F multipurpose (45° tip) diagnostic vascular catheter was inserted. Once the pelvi¬ureteric junction was crossed and the ureter accessed, a straight hydrophilic guidewire and a catheter were used. Then, the cath-eter was advanced into the bladder over the wire, this guidewire was exchanged for an ultra-stiff guidewire, an 8 or 10 F double J ureteral stent was placed over the guidewire, and the safety kit of the stent was removed. A final fluoroscopic image was stored for correcting the stent position.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Université de Sousse

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	number of patient having Antegrade double-J stent placement for the treatment of malignant obstructive uropathy	double j stent placement succeed or failed	7 years