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Urologic Injuries clinical trials

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NCT ID: NCT04835766 Recruiting - Bladder Dysfunction Clinical Trials

Urodynamic Changes Following Bladder Injury

Uro-PAS
Start date: July 1, 2021
Phase:
Study type: Observational

This study is a unique one as it si done for first time to all patients following bladder injury in PAS surgery. Bladder function will be assessed by urodynamic study.

NCT ID: NCT04162782 Not yet recruiting - Urologic Injuries Clinical Trials

Urological Injuries During Obstetric and Gynecological Operations

Start date: December 1, 2019
Phase:
Study type: Observational

Iatrogenic urinary tract injuries are more common during obstetric and gynaecological procedures averaging 2.6 per 1000 surgeries . The objective of the study is to estimate the incidence of iatrogenic urinary tract injuries and risk factors during obstetric and gynaecological operations. Embryologically, the urinary system and genital system have a common origin, so anatomically they are so close that predisposes to iatrogenic trauma to it during obstetric and gynaecological operations. The bladder and distal ureters are the most commonly involved organs. The bladder is a retroperitoneal structure, its trigone rests over the anterior vaginal fornix and the base rests on lower uterine segment and cervix.

NCT ID: NCT03240822 Withdrawn - Amputation Clinical Trials

Human Penile Tissue Allotransplantation for Devastating Penile and Concomitant Genital Trauma

Start date: January 2017
Phase: Phase 1
Study type: Interventional

This is a 4-year, non-randomized, single center, patient self-controlled, clinical trial (though enrolled subjects will be followed for life as are all transplant patients) for patients seeking allotransplantation of the male external genitalia (MEG), or penile tissue, as a feasible reconstructive strategy for the treatment of devastating and irreversible injuries to the genitalia. In addition to receiving penile allotransplantation and post-operative monitoring and support, enrolled patients will receive an innovative and clinically proven immunomodulatory protocol that combines lymphocyte depletion of the recipient with donor bone marrow cell infusion. Patients will be treated with lymphocyte depleting induction therapy, donor bone marrow cell infusion and tacrolimus. After the first year, maintenance immunosuppression will be modified gradually and cautiously (tapered dose reduction or spaced frequency dosing of tacrolimus) in selected patients based on a critical evaluation of clinical and immunologic outcomes. Outcomes will include but not be limited to functional metrics (sensation, erection, voiding), psychosocial (body integrity, adaptation to transplant) and health related quality of life (HRQOL) measures.

NCT ID: NCT03108079 Recruiting - Clinical trials for Urinary Incontinence

Bladder Morphology Using 2 Different Catheter Designs

Start date: April 2017
Phase: N/A
Study type: Interventional

Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)

NCT ID: NCT02007980 Active, not recruiting - Kidney Calculi Clinical Trials

Indwelling Stent Discoloration Project

Start date: December 2013
Phase:
Study type: Observational

The aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.