Urogynecologic Surgery Clinical Trial
Official title:
Comparing Methods of NSAID Delivery for Postoperative Pain
Specific Aim 1: To identify differences in pain perception and satisfaction with pain control in women undergoing urogynecologic surgery receiving nonsteroidal anti-inflammatory (NSAIDS) postoperatively by oral ibuprofen, intravenous ibuprofen, or intravenous ketorolac. Specific Aim 2: To compare the differences in narcotic usage and medication side effects.
All patient will be informed that they may receive either ibuprofen or ketorolac and that
the medication may be given (IV) or per os (PO). Patients were also informed that their pain
may improve or worsen during the study, and that they could request additional pain
medication (as a rescue medication) at any time.
After surgery, all patients will be placed initially on a patient controlled analgesia (PCA)
of hydromorphone with standardized settings of allowing the patient to dispense 0.2 mg of
medication every 6 minutes (lockout rate) and an hourly maximum of 2.0 mg/hour. A one-time
nursing bolus of 0.4 mg will also be ordered. The PCA will be discontinued on the morning
after surgery no later than 12:00 noon. The patient will then be started on PO pain
medication, either hydrocodone/acetaminophen or oxycodone/acetaminophen.
Immediately after surgery, patients will then be assigned to one of three treatment arms
with a computer-generated randomization schedule that is to be based on their order of
enrollment. Patients were informed they could withdraw at any point. Three visual analog
scores (VAS) will be obtained from the patient before noon on the first day after surgery.
One scale to assess pain at rest, one scale to assess pain with ambulation, and one scale to
assess satisfaction with pain control.
The medications will each be given every 8 hours in order to keep all medications on a
similar doing regimen. This will allow the patients to receive a total of three doses of
medication over 24 hours, regardless of which arm of the study they are randomized to.
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Observational Model: Case-Only, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03178734 -
Foley Catheter vs a Self-contained Valved Urinary Catheter
|
N/A |