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Urine clinical trials

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NCT ID: NCT05746130 Completed - Adolescent Behavior Clinical Trials

Effect of Preventive Education on Reducing Urinary Bisphenol-A Levels in Adolescents

Start date: March 16, 2023
Phase: N/A
Study type: Interventional

It is known that Bisphenol-A (BPA) is the endocrine disrupting chemical that is most exposed by oral intake in daily life. Critical life periods when the sensitivity to these substances is known to be maximum; prenatal, postnatal and adolescence periods. The aim of this study is to compare the effects of plastic-free nutrition program, interactive education and BPA exposure feedback on urinary Bisphenol-A levels in adolescents with high use of packaged products.

NCT ID: NCT04530201 Completed - Cervical Cancer Clinical Trials

CASUS: Validation for Detection of Precursor Lesions

CASUS-WP4
Start date: August 20, 2020
Phase: N/A
Study type: Interventional

The goal of the overall CASUS project is to develop the first fully molecular integrated cervical cancer screening approach, based on first-void urine as an easily accessible and non-invasive source of biomarkers. In contrast to current screening modalities, the CASUS approach will identify women with clinically relevant disease in need of treatment using only a single sample that can be collected at home (one-step triage).

NCT ID: NCT04480866 Completed - Cervical Cancer Clinical Trials

CASUS: Improved and Quality Assured Collection of First-void Urine

CASUS-WP1
Start date: July 30, 2019
Phase: N/A
Study type: Interventional

The goal of the overall CASUS project is to develop the first fully molecular integrated cervical cancer screening approach, based on first-void urine as an easily accessible and non-invasive source of biomarkers. In contrast to current screening modalities, the CASUS approach will identify women with clinically relevant disease in need of treatment using only a single sample that can be collected at home (one-step triage).

NCT ID: NCT04446169 Completed - SARS-CoV 2 Clinical Trials

COVID-19 (SARS-CoV-2) in Urine and Semen

Start date: June 27, 2020
Phase:
Study type: Observational

This study is part of the current global emergency scenario due to infection with Coronavirus, SARS-CoV-2 as indicated by the international taxonomy. Study aim is to investigate the possibility of the presence of the virus within the seminal fluid and in the urine of infected patients, both during the acute phase and remotely. Current evidences show that Coronaviruses can be present inside the testicle and sperm in other species, such as in feline and avian models. In human beings, current researches have mixed results regarding the presence of SARSCoV-2 in urine, as several studies with a large sample found no traces of the same with Real-Time Reverse method Transcriptase - Polymerase Chain Reaction or with method of nucleic acid amplification. By contrast, in just over 6% of 58 patients with Real Time Polymerase Chain Reaction method have found the presence of SARS-CoV-2 in the urine, even at a distance from the last negative nasopharyngeal swab. Given the topicality of the problem, our study has the objective of specifically researching the presence and possible persistence over time of SARS-CoV-2 in seminal fluid and urine. A saliva sample will also be collected as a control. At the moment there are no studies in literature that tested this possibility. If confirmed, it would lead to find out another potential method of transmission, the sexual one, in asymptomatic patients or apparently no longer infectious with negative buffer. The rationale for our study is the evidence that in other species this type of transmission by coronaviruses is possible and that at present it has not been verified in mankind. The relevance of the study would be both in the case of a negative result, as the first study in its generally, both in the case of a positive result, due to the possibility of introducing new prevention measures in the long run.

NCT ID: NCT03066310 Completed - Bladder Cancer Clinical Trials

Urine-DNA Biomarkers in Detecting Bladder Cancer

Start date: January 17, 2017
Phase:
Study type: Observational

DNA biomarkers in urine are important diagnostic and prognostic indicators for bladder cancer. Many genetic alterations have been identified in the urinary DNA. However, not all bladder tumors harbor mutations in the most commonly altered oncogenes. Thus, to reach satisfactory sensitivity and specificity a new diagnostic test should include multiple biomarkers. The investigators will conduct a prospective evaluation of a panel of mutations in urine-DNA test for the detection of urothelial bladder carcinoma in patients with gross hematuria for cystoscope.

NCT ID: NCT00383981 Completed - Urine Clinical Trials

Lipid Peroxidation in Workers Exposed to Al,Ga,In,As,and Sb in Optoelectronic Industry

Start date: March 2003
Phase: Phase 1
Study type: Observational

To investigate whether exposure to Al, Ga, In, As, and Sb induces lipid peroxidation in humans. Whole blood and urine levels of 170 workers were analysed by use of ICP-MS. MDA, the product of lipid peroxidation was determined by HPLC