Biological Variability in Cartilage Specific Biomarkers in Healthy Volunteers. — COVAR  

Urine Marking Clinical Trial

Official title: Evaluation of Biological Variability in Cartilage Specific Biomarkers (Coll2-1, Coll2-1NO2, FIB3-1 and FIB 3-2) in Healthy Volunteers.

Status Completed

Clinical Trial Summary

The purposes of the study are to assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage.

Clinical Trial Description

To assess intra individual biological variability of serum and urinary cartilage specific biomarkers and define the best standardized conditions for blood and urine sampling in the frame of biomarkers dosage. Variation factors assessed are:

• Fasting condition

• Sampling time

• Sampling season

• Physical activity

• Duration and temperature of total blood treatment

• Type of blood collection tube. ;

Study Design

Observational Model: Cohort

Related Conditions & MeSH terms

• Effects of; Serum
• Urine Marking

• NCT number: NCT02348944
• Study type: Observational
• Source: Artialis
• Status: Completed
• Phase: N/A
• Start date: August 2013
• Completion date: December 2014