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Urinary Retention clinical trials

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NCT ID: NCT04187365 Terminated - Urinary Retention Clinical Trials

Optimizing the Management of Postpartum Urinary Retention

PUR
Start date: November 22, 2019
Phase: N/A
Study type: Interventional

A study aimed at characterizing the comparing duration of catheterization for treatment of postpartum urinary retention (PUR) and characterizing short and long-term pelvic floor symptoms in women who have PUR.

NCT ID: NCT04159077 Not yet recruiting - Thoracic Surgery Clinical Trials

REduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial

REPOURT-P
Start date: July 30, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study are to determine the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention and improving other clinical outcomes in people undergoing thoracic surgery.

NCT ID: NCT04104165 Completed - Retention, Urinary Clinical Trials

Treatment of Postpartum Urinary Retention

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate what is the most effective catheterization duration to resolve covert and overt postpartum urinary retention following vaginal delivery and caesarean delivery, with the highest patients' satisfaction.

NCT ID: NCT04059159 Terminated - Urinary Retention Clinical Trials

Connected Catheter - Safety and Effectiveness Study

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The Connected Catheter is a fully internal, urethral indwelling urinary prosthesis designed for improved bladder management in males with urinary retention disorders requiring catheterization. It is a sterile, extended-use device that resides fully internally to the male lower urinary tract for an intended use life of up to 7 days per catheter.

NCT ID: NCT04030377 Terminated - Urinary Retention Clinical Trials

Postop Catheterization for Urinary Retention

Start date: April 2010
Phase:
Study type: Observational

This study investigates patient's preference and satisfaction with choice of catheterization after surgical urogynecological procedures.

NCT ID: NCT04010656 Active, not recruiting - Voiding Disorders Clinical Trials

Optimization of Spontaneous Postoperative Trial of Void Among Women

OPTION
Start date: September 10, 2018
Phase: N/A
Study type: Interventional

Trial of void (TOV) is a diagnostic test performed on all women who undergo prolapse repair or incontinence surgery, due to the importance of diagnosing postoperative urinary retention (POUR). Incidence of POUR may be as high as 62% in some studies. Timely and accurate diagnosis is important to avoid complications such as urinary tract infection, bladder overdistension, and permanent bladder injury. Despite the frequent use of TOV, there is no gold standard for the test, and it likely has poor specificity, leading to discharge of more patients with catheter than required. This prospective cohort study will seek to establish evidence-based optimal parameters for spontaneous trial of void, a TOV modality that has merit for further evaluation given lower theoretical risk of urinary tract infection.

NCT ID: NCT04000763 Recruiting - Urinary Retention Clinical Trials

Superficial Peroneal Nerve Neuromodulation for Non-Obstructive Urinary Retention

Start date: December 20, 2019
Phase: N/A
Study type: Interventional

Millions of Americans are suffering from underactive bladder (UAB). The impact of severe UAB, i.e. non-obstructive urinary retention (NOUR) on quality of life is significant because current treatment for non-obstructive urinary retention requires intermittent self-catheterization or an indwelling suprapubic catheter. Currently an effective drug for non-obstructive urinary retention does not exist. It is a therapeutic challenge for clinicians to successfully treat non-obstructive urinary retention. Sacral neuromodulation has been approved by the FDA since 1999 to treat non-obstructive urinary retention. It achieves >50% improvement in bladder emptying (reducing the frequency of self-catheterization or increasing voided volume) in just over half of the patients. Sacral neuromodulation requires surgical implantation of a stimulator and a lead with 4 electrodes. The surgery and implant are invasive and expensive, preventing a broad application of this effective therapy to many non-obstructive urinary retention patients. The goal of this study is to develop a novel non-invasive neuromodulation therapy for non-obstructive urinary retention as an alternative. Specifically, the investigators will explore the possibility to translate into humans a recent discovery in cats of an excitatory reflex from the superficial peroneal nerve to the bladder to treat non-obstructive urinary retention. Therefore, in this study the investigators propose to develop a non-invasive, transcutaneous neuromodulation therapy for non-obstructive urinary retention that can be administered at home.

NCT ID: NCT03976934 Completed - Inguinal Hernia Clinical Trials

Prophylactic Administration of Alpha Blockers for Prevention of Urinary Retention in Males Undergoing Inguinal Hernia Repair Under Spinal Anaesthesia.

Start date: February 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Open inguinal hernia repair is one of the most common surgical procedures. Despite the fact that different of anesthetic procedures are proposed as alternatives to spinal anesthesia, the combination of spinal anesthesia with open inguinal hernia repair is preferred from both surgeons and patients. One disadvantage of this combination is the high incidence of post-surgery urinary retention, especially in men above 50 years old. This complication is partially attribute to overstimulation of the a1 adrenergic receivers of the bladder and the prostate. Preoperative administration of elective a1 blockers could inhibit this effect without side effects, since this drugs don't have systemic effect.

NCT ID: NCT03958279 Terminated - Urinary Retention Clinical Trials

Normal and Pathological Values of Postvoiding Residual Volume in Early Postpartum Period and Their Predisposing Factors

PAREZ
Start date: February 1, 2018
Phase:
Study type: Observational

Aim of this study is to asses post voiding residual volume by ultrasound scan 3th day after delivery with consecutive scan after 6 weeks, and determination of data dispersion among the population of primiparas. In women with excessive retention (+2SD), risk factors such as duration of labour, use of epidural analgesia, instrumental delivery, maternal birth injury and weight of the newborn will be noted down.

NCT ID: NCT03937531 Withdrawn - Clinical trials for Postoperative Urinary Retention

Void Trials After Two Voiding Trials (TVT)

Start date: February 2020
Phase: N/A
Study type: Interventional

The primary objective of this project is to compare the rate of postoperative voiding dysfunction in two voiding trials (the retrograde-fill technique versus the spontaneous-fill technique) after midurethral sling (MUS) procedures with tension-free vaginal tape (TVT) without any concomitant surgery.