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Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium

Urinary Incontinence Clinical Trial

Official title:
A Quantitative Analysis of Protein- and mRNA-Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium

Clinical Trial Summary

Painful bladder syndrome (PBS)/interstitial cystitis (IC) may be due to the actions of nitric oxide (NO) in the bladder tissue. NO is a gaseous substance with a very short half-life, synthesized by a group of NO-synthase-enzymes in many tissues.

The goal of this study is to illuminate bladder tissue production of NO in individuals with PBS and healthy individuals, by quantification of NO and NO-enzyme expression by different molecular biological methods.

Clinical Trial Description

n/a

Study Design

Observational Model: Defined Population, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00253006
Study type Observational
Source Copenhagen University Hospital at Herlev
Contact
Status Terminated
Phase N/A
Start date January 2006
Completion date January 2008
View Details
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