Compare the Therapeutic Effect Treated With Tamsulosin and Progesterone After ESWL( Extra Corporeal Shock Wave Lithotripsy) in Urinary Calculus

Urinary Calculus Clinical Trial

Official title:

the Therapeutic Effect Treated With Tamsulosin After ESWL in Urinary Calculus

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01010048
• Other study ID #: CQMU
• Status: Recruiting
• Phase: Phase 4
• First received: November 6, 2009
• Last updated: November 12, 2009
• Start date: October 2009
• Est. completion date: December 2010

Study information

• Verified date: November 2009
• Source: Chongqing Medical University
• Contact: Yunfeng He, Doctor
• Phone: 86-23-89011121
• Is FDA regulated: No
• Health authority: China: Food and Drug Administration
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to compare the stone clearance rate treated with different drugs after ESWL in urinary calculus,These drugs are often used in urinary calculus,such as progesterone,tamsulosin,propantheline Bromide and nifedipine.In these study the investigators want to investigate different effect of these drugs use to treat urinary calculus after ESWL.

Description:

There is 4 groups in these investigation, group1 urinary calculus treated with ESWL only ,group2 urinary calculus treated with ESWL and tamsulosin,group3 urinary calculus treated with ESWL and progesterone,group4 urinary calculus treated with ESWL ,propantheline Bromide and nifedipine.We want to investigate which one is better or not in urinary calculus treated with ESWL .

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: December 2010
• Est. primary completion date: October 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 68 Years

Eligibility

Inclusion Criteria:

• From 18 years old to 68 years old,

• urinary calculus could be treated by ESWL,

• the calculus size is from 4-25mm

Exclusion Criteria:

• Less than 18 years old or more than 68 years old,

• the calculus size is from Less than4 or larger than 25mm

Study Design

Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Calculi
• Urinary Calculi
• Urinary Calculus

Intervention

Drug:
• progesterone,tamsulosin,propantheline Bromide and nifedipine
clearance rate of stone

Locations

Country	Name	City	State
China	The First Affiliated Hospital, ChongQing medical University	ChongQing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Chongqing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	different effect of these drugs use to treat urinary calculus after ESWL		2weeks	Yes