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Urinary Bladder, Overactive clinical trials

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NCT ID: NCT04450511 Completed - Clinical trials for Urge Incontinence Episodes After the Magnetic Stimulation Added to Bladder Training in Women With Idiopathic Overactive Bladder

Pelvic Floor Magnetic Stimulation in Women With Idiopathic Overactive Bladder

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

In clinical practice, Bladder Training (BT) and Magnetic stimulation (MS) are frequently used together in the treatment of women with idiopathic overactive bladder (OAB). Up to our knowledge, there is no study evaluating the combined effect of magnetic stimulation and bladder training in women with idiopathic OAB in the literature. Moreover, there is no recommendation on conservative treatment combinations in the guidelines due to insufficient data. At this stage, studies are needed to determine whether it will be effective to use MS in combination with other conservative treatment options. In addition, in the light of our clinical experience, we think that this issue is still open for research. In our study, adding MS to BT in women with idiopathic OAB is thought to contribute additionally to the efficacy of treatment with BT. Our study is the first prospective randomized controlled trial that compares the efficacy of BT and BT plus MS in women with idiopathic OAB. In this study, we aimed to evaluate the efficacy of MS added to BT on incontinence-related QoL and clinical parameters in women with idiopathic OAB.

NCT ID: NCT04437108 Completed - Overactive Bladder Clinical Trials

Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPO

Start date: July 4, 2020
Phase: N/A
Study type: Interventional

comparing the outcome of low-intensity shock wave therapy (Li-SWT) versus solifenacin on persistent storage symptoms after transurethral surgery for benign prostatic obstruction (BPO)

NCT ID: NCT04423744 Completed - Endometriosis Clinical Trials

Study to Gather Information on the Influence of BAY1817080 on the Electrical Activity of the Heart Recorded by an Electrocardiogram in Healthy Male and Female Participants

Start date: June 18, 2020
Phase: Phase 1
Study type: Interventional

In this study, researchers want to find whether the study drug BAY1817080 has an effect on the electrocardiogram (ECG). 40 healthy male or female participants with the age of 18 to 65 years will be enrolled into this study. The ECG of the participants will be monitored closely by the researchers to detect any change after intake of the study medication.

NCT ID: NCT04420533 Completed - Sexual Behavior Clinical Trials

Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron in Sexually Active Men With OAB Symptoms

Start date: June 5, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate and compare the therapeutic effects on OAB symptoms, and sexual functions, in terms of erectile function and ejaculatory function, in sexually active OAB male treated with behavior therapy or behavior therapy plus Mirabegron (50 mg).

NCT ID: NCT04412928 Completed - Clinical trials for Stress Urinary Incontinence

Factors Affecting the Cure of Overactive Bladder Syndrome in Women Underwent Mid-urethral Sling Procedure

Start date: April 13, 2020
Phase:
Study type: Observational

We will estimate the incidence of patients with overactive bladder syndrome after surgery and explore related predictors.

NCT ID: NCT04389307 Completed - Clinical trials for Electrical Stimulation

Intravaginal Electrical Stimulation in Idiopathic Overactive Bladder

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

Overactive bladder (OAB) is a symptom complex defined as urgency, with or without urge urinary incontinence (UUI), usually with frequency and nocturia, in the absence of urinary tract infection. Currently, a wide range of therapeutic options exist for the treatment of OAB. These include first-line conservative (physical) therapies which focus on electrical stimulation (ES) and behavioral therapies such as lifestyle modifications, bladder training (BT), pelvic floor muscle training with or without biofeedback, second-line therapies which are pharmacologic, and third-line therapies which either neuromodulate or chemodenervate the bladder. In clinical practice, BT and Intravaginal ES (IVES) are frequently used together in the treatment of women with OAB, but the evidences/results of the combined (BT+IVES) use of these two treatment options are so rare that they can be neglected in the literature. There is only one study including BT+ES treatment arm (one of the four treatment arms) in women with idiopathic OAB in the literature. In a study, BT+ES was not found to be effective both from BT alone and from the untreated control group. While interpreting the results of this study, it should be take into consideration that patients treated received relatively few treatment sessions (nine treatment sessions, once weekly) in this study. In addition, in the light of authors clinical experience, the investigators think that this issue is still open for research. Moreover, there is no recommendation on conservative combinations in the guidelines due to insufficient data. This study is the first prospective randomized controlled trial that compares the efficacy of BT and BT plus IVES in women with idiopathic OAB. In this study, the investigators aimed to evaluate the efficacy of BT with and without IVES on incontinence-related QoL and clinical parameters in women with idiopathic OAB.

NCT ID: NCT04369404 Completed - Overactive Bladder Clinical Trials

Impact of Decision Aids in Urogynecology

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

To evaluate how patient knowledge and confidence in decision making can be impacted by shared decision making in common urogynecology conditions.

NCT ID: NCT04309890 Completed - Overactive Bladder Clinical Trials

Arabic Translation and Validation of the (Overactive Bladder Symptom Score) OABSS

Start date: February 1, 2019
Phase:
Study type: Observational

The English version of the Overactive Bladder Symptom Score (OABSS) questionnaire was translated to Arabic language. The questionnaire was validated by comparing the response to the questionnaire in a patient with Overactive Bladder (OAB) before and after providing treatment with antimuscarinics.

NCT ID: NCT04300400 Completed - Clinical trials for Overactive Bladder Syndrome

Treatment of the Overactive Bladder Syndrome: A Delphi Study

Start date: October 16, 2018
Phase:
Study type: Observational

Idiopathic overactive bladder syndrome (iOAB) is a prevalent condition in urological practice. The variability in management between specialists and between centers remains high. Even guidelines are not always clear on the treatment management of drug therapy resistant OAB. Standardization in OAB treatment is needed.

NCT ID: NCT04270526 Completed - Overactive Bladder Clinical Trials

Minimizing Pain During Office Intradetrussor Botox Injection

Start date: August 15, 2020
Phase: Phase 4
Study type: Interventional

This will be a prospective double-blinded randomized controlled trial comparing two pre-treatment protocols for patients undergoing intradetrussor botox injections to determine if a buffered lidocaine solution offers superior pain control.