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Urinary Bladder, Overactive clinical trials

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NCT ID: NCT02501928 Completed - Clinical trials for Urinary Bladder, Neurogenic

Open-label Long-term Extension Study of Fesoterodine in Japanese Subjects With Neurogenic Detrusor Overactivity.

Start date: June 5, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the safety and tolerability of fesoterodine following once daily long-term treatment in Japanese pediatric neurogenic detrusor overactivity (NDO) subjects.

NCT ID: NCT02495389 Completed - Overactive Bladder Clinical Trials

Mirabegron and Urinary Urgency Incontinence

Start date: January 28, 2015
Phase: Phase 4
Study type: Interventional

This study is for women diagnosed with urinary urgency incontinence (UUI) or overactive bladder (OAB). Some patients continue to have symptoms even while taking medication for OAB. The purpose of this study is to estimate the number of women who respond to a medication called mirabegron and estimate change in symptom severity over 12 weeks of therapy. A secondary goal is to correlate the female urinary microbiome (FUM) with response to treatment and change in symptom severity over 12 weeks of therapy.

NCT ID: NCT02494349 Completed - Overactive Bladder Clinical Trials

The PK Study of the JLP-1207 and Solifenacin/Tamsulosin in Healthy Male Volunteers.

Start date: August 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate and compare the pharmacokinetic characteristics and safety/tolerability between JLP-1207(Solifenacin/Tamsulosin 5mg/0.2mg)and co-administration of Solifenacin and Tamsulosin between Solifenacin and Tamsulosin in healthy male volunteers.

NCT ID: NCT02485067 Completed - Overactive Bladder Clinical Trials

Clinical Study to Assess the Efficacy and Safety of THVD-201 in Patients With OAB

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to assess the efficacy and safety of THVD-201(Combination of tolterodine and pilocarpine) in patients with Overactive bladder during the period of treatment, 12 weeks. This study also includes an open label extension period of an additional 12 weeks following the treatment to assess long-term efficacy and safety of THVD-201 in patients with Overactive bladder.

NCT ID: NCT02476175 Completed - Clinical trials for Urinary Incontinence

Add-on Mirabegron in Pediatric Patients With Refractory Overactive Bladder

Add-on-Mira
Start date: April 2013
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the efficacy and safety of adding mirabegron to an antimuscarinic to treat urinary incontinence in children with Overactive Bladder that are refractory to antimuscarinics.

NCT ID: NCT02468830 Completed - Clinical trials for Urinary Incontinence

Pilot Study of Mirabegron in Pediatric Patients With Overactive Bladder

Mirabegron
Start date: April 2013
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the efficacy and safety of mirabegron to treat urinary incontinence in children with Overactive Bladder that are refractory and/or intolerant to antimuscarinics.

NCT ID: NCT02468375 Completed - Overactive Bladder Clinical Trials

Prospective Study for Patient Perception of Treatment Satisfaction After Switching to Mirabegron in Patients With Overactive Bladder Who Were Unsatisfied With Efficacy of Antimuscarinic Therapy or Adverse Event.

Start date: June 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to measure the treatment satisfaction after switching to mirabegron in patient with Overactive Bladder(OAB) who were unsatisfied with efficacy of antimuscarinic therapy or adverse event. Patient will take the mirabegron 50mg/day for 12 weeks, and the satisfation of the therapy will be measured with Treatment Satisfaction Questionnaire(TSQ), Global Response Assessment(GRA), OAB-q short form, OAB Symptom Score and Willingness to continue Questions.

NCT ID: NCT02447367 Completed - Overactive Bladder Clinical Trials

Investigate the Effect of Food on the Pharmacokinetic of JLP-1207 in Healthy Male Volunteers

Start date: July 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the pharmacokinetic drug interaction between Solifenacin and Tamsulosin in healthy male volunteers.

NCT ID: NCT02396160 Completed - Clinical trials for Urinary Incontinence

The Effect of Urox™ in the Treatment of Overactive Bladder and Urinary Incontinence

Start date: August 2013
Phase: N/A
Study type: Interventional

This study aims to assess the efficacy of a specialized herbal formula, Urox, versus control over 8 weeks, in a double blind, placebo controlled trial. 150 participants are being recruited, randomized and administered treatment or placebo for the period of 8 weeks after initial eligibility screening. Outcome measures include previously validated tools such as the 3 day symptom diary measuring self-recorded day frequency, nocturia, urgency and incontinence episodes. Quality of life improvements are being measured using the Incontinence Impact Questionnaire, Urinary Distress Inventory and the short version of the OverActive Bladder survey.

NCT ID: NCT02386072 Completed - Overactive Bladder Clinical Trials

A Prospective, Observational, Multicenter Study of Patients Following Initiation of a New Course of Treatment for Overactive Bladder (OAB)

PERSPECTIVE
Start date: January 5, 2015
Phase:
Study type: Observational

A study to identify factors that are associated with improved effectiveness in pharmacologic therapy of Overactive Bladder, from the patient perspective primarily measured by OAB-Q-SF (Overactive Bladder Questionnaire Short Form)