Urinary Bladder, Neurogenic Clinical Trial
Official title:
A Randomized Trial of Transcutaneous Nerve Stimulation for Neurogenic Bladder
Neurogenic bladder patients may have symptoms of urinary frequency, urgency, urgency incontinence and voiding symptoms due to bladder dysfunction arising from their underlying neurologic condition. Current treatment options are effective for some patients, however many patients are not optimally managed due to modest efficacy or significant side effects. Second line therapies include intravesical onabotulinum toxin, however it is associated with a risk of urinary retention, and patients with neurologic disorders often are unable to perform self catheterize due to physical limitations. Sacral neuromodulation is associated with an undesirably high cost and potential complications in this population. The use of transcutaneous tibial nerve stimulation is an alternative form of neuromodulation, and it may have some potential benefits over percutaneous tibial nerve stimulation. While some preliminary studies have suggested it may be effective, there are no high quality randomized trials. This proposal is a 3 month, randomized, sham-controlled, clinical trial to evaluate the short term clinical efficacy of at home transcutaneous tibial nerve stimulation. Valid and reliable patient reported outcome measures, and objective measures of incontinence have been included as outcomes.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05141487 -
Feasibility of Triggered Sacral Neuromodulation for Neurogenic Bladder
|
||
| Completed |
NCT01920243 -
Evaluation of a Bowel and Bladder Health Management Program for Individuals With Spinal Cord Injury (SCI)
|
N/A | |
| Completed |
NCT04528784 -
Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple Sclerosis
|
N/A | |
| Enrolling by invitation |
NCT03336424 -
Urinary Disorders in Patients With Multiple Sclerosis: Invasive Vs Non-invasive Investigations.
|
N/A | |
| Not yet recruiting |
NCT05075642 -
Multicenter Observational Study for the Evaluation in Clinical Practice of Urinary Disorders in Multiple Sclerosis
|
||
| Completed |
NCT02600715 -
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
|
Phase 4 | |
| Recruiting |
NCT04128709 -
Measurement of Bladder Pressure With a Novel External Device (Cystomanometer) - Home Use
|
N/A | |
| Enrolling by invitation |
NCT05740527 -
Ambulatory Closed-loop Stimulation for Bladder Control
|
N/A | |
| Completed |
NCT02501928 -
Open-label Long-term Extension Study of Fesoterodine in Japanese Subjects With Neurogenic Detrusor Overactivity.
|
Phase 3 | |
| Recruiting |
NCT06336304 -
NXT Post-Market Clinical Follow-up
|
||
| Completed |
NCT06445426 -
Cystometry Using a Novel Microsensor System in Patients With Neurogenic Bladder Dysfunction
|
||
| Recruiting |
NCT04819360 -
Botulinum Toxin A vs Anticholinergic Treatment of Neurogenic Overactive Bladder in Patients With Multiple Sclerosis
|
Phase 4 | |
| Terminated |
NCT02044510 -
Urodynamic and Clinical Efficacy of Mirabegron for Neurogenic Bladder Patients
|
Phase 2/Phase 3 | |
| Completed |
NCT01557244 -
A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurological Condition
|
Phase 3 | |
| Recruiting |
NCT05380661 -
Heart Rate Variability and Anxiety During Urinary Bladder Catheterization
|
N/A | |
| Recruiting |
NCT04193709 -
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
|
N/A | |
| Active, not recruiting |
NCT05232253 -
Cystoealstometer (Bladder Monitor Device)-Home Use
|
N/A | |
| Completed |
NCT03405285 -
Connected Catheter Clinical Feasibility Study( CFS)
|
N/A | |
| Completed |
NCT02673047 -
Observational Study of Botulinum Toxin Type A in Patients With Urinary Incontinence Associated With Overactive Bladder
|
N/A | |
| Completed |
NCT01773213 -
Detrusor Contraction During the Ice-water-test
|
N/A |