Direct Full-stage Implantation of Sacral Neuromodulation

Status Withdrawn

Clinical Trial Summary

The purpose of this investigator-initiated study is to investigate the efficacy and costs of direct full stage sacral neuromodulation in patients with overactive bladder. Patients with refractory OAB and urge urinary incontinence will undergo direct full stage implantation and be followed for a period of 6 months to monitor symptom improvement with voiding diaries and validated questionnaires preoperatively and postoperatively. Therapeutic and adverse outcomes will be evaluated. The use of medical resources and time off of work will be analyzed as well. This will be a descriptive study with no additional arms or randomization.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03697954
Study type	Observational
Source	Loma Linda University
Contact
Status	Withdrawn
Phase
Start date	May 2021
Completion date	December 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06201013` - Efficacy and Safety of Vitamin D in the Treatment of OAB-wet in Children	N/A
Recruiting	`NCT05880862` - Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls	Early Phase 1
Recruiting	`NCT04807920` - BOTOX® at the Time of Prolapse Surgery for OAB	Phase 4
Terminated	`NCT02385500` - Fesoterodine on Urgency Episodes in Parkinson's Disease Population	Phase 4
Not yet recruiting	`NCT02477241` - Brain Areas Involved in Bladder Filling and Contraction	N/A
Completed	`NCT01698138` - Prevention of Bladder Dysfunction in Acute Spinal Cord Injury	Phase 4
Completed	`NCT00527033` - A Study of YM178 in Patients With Symptomatic Overactive Bladder	Phase 2
Completed	`NCT00613327` - An Efficacy and Safety Study of Oxybutynin Chloride Oral Osmotic Therapeutic System (OROS) in Korean Overactive Bladder Participants	Phase 4
Completed	`NCT00368706` - A Double-Blind, Paralleled Study Comparing Efficacy/Safety of Solifenacin to Tolterodine in Overactive Bladder Patients	Phase 3
Recruiting	`NCT04305743` - Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A	Phase 4
Active, not recruiting	`NCT03681678` - Laser Therapy for Treatment of Urogenital Symptoms in Women
Completed	`NCT01655069` - A Study to Investigate How Safe and Effective Solifenacin Solution is in Treating Children/Adolescents With Symptoms of Overactive Bladder (OAB) Who Completed Study 905-CL-076	Phase 3
Completed	`NCT01558856` - Unilateral Versus Bilateral Neuromodulation Tests in the Treatment of Refractory Idiopathic Overactive Bladder	N/A
Completed	`NCT01521767` - Pharmacokinetics and Relative Bioavailability Study	Phase 1
Completed	`NCT01157377` - Safety and Efficacy Study of AGN-214868 in Patients With Idiopathic Overactive Bladder and Urinary Incontinence	Phase 2
Completed	`NCT01194999` - Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence	Phase 4
Completed	`NCT01381120` - Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms	Phase 4
Completed	`NCT01262391` - Single-dose Study to Assess Pharmacokinetics of Solifenacin Succinate Suspension in Children and Adolescents	Phase 1
Completed	`NCT04528784` - Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple Sclerosis	N/A
Completed	`NCT02849418` - Efficacy and Safety Study of GSK1358820 in Japanese Patients With Urinary Incontinence Due to Neurogenic Detrusor Overactivity	Phase 3