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Urethra Injury clinical trials

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NCT ID: NCT03204201 Terminated - Surgery Clinical Trials

Validation of ICG to Identify the Urethra During Rectal Surgery

Start date: July 11, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label feasibility study utilising direct instillation of ICG into the urethra during surgery for low rectal cancers. The trial involves a single intervention taking place during the patient's operation. Participants will be included in the study for around 2 months with time either side of the intervention to collect background data.

NCT ID: NCT03118284 Terminated - Clinical trials for Catheter Site Discomfort

Foley Catheter Related Bladder Discomfort (FCRBD): Role of Neutrophil Cells

FCRBD
Start date: November 21, 2016
Phase:
Study type: Observational

Urinary [Foley] catheters [tubes] are commonly placed in patients undergoing surgery; approximately 25% of surgical patients will receive one. Among patients who receive urinary catheters, discomfort associated with the Foley catheter is common; between 47-90% of patients experience catheter related bladder discomfort [CRBD]. Presence of a foreign object in the bladder even for short periods of time may result in symptoms such as a burning sensation, pain in the lower abdomen, muscle spasms and a sense of urgency to urinate. There is some evidence that suggests that hospital-acquired urinary tract infections are directly related to catheter placement, which causes mechanical damage and local inflammation to the urethra and the bladder. Based on research conducted on a similar mechanism where an airway tube is inserted into a patients throat for delivery of general anesthesia - we hypothesize that CRBD is related to injury and inflammation caused by the catheter placement and that this occurs in a sterile environment.