Apnea, Obstructive Clinical Trial
Official title:
Comparison of Techniques to Improve Oxygenation and Capnographic Detection During Sedative Gastrointestinal Endoscopy
The purpose of this study is to compare the effect of mandibular advancement bite block and high flow nasal cannula to standard bite block for oxygenation, capnographic measurement, prevention of hypoxemia, intervention events and adverse effects during endoscopic examinations.
During endoscopic examinations, especially during those performed via oral insertion of endoscopes, an oral bite is used to protect the examination instruments and patients. During sedated endoscopic examinations, the patients are under influence of anesthetics. Upper airway obstruction often occurred due to respiratory depression and airway collapse resulting in desaturation. Airway management with high percentage oxygen, jaw thrust, or insertion of nasal airways by trained anesthetic personnel is required during upper airway obstruction emergencies. Nasal airway is invasive and causes nasal bleeding, sinusitis and other problems. Jaw thrust and bag-mask ventilation requires training and is a burden to anesthetic personnel to perform. Oxygenation and capnography are important ventilatory monitors during sedative procedures. These are often influenced by open mouth breathing during upper gastrointestinal endoscopic examinations making oxygenation and capnographic measurements unreliable. In this study, we group the patients into A group using standard of care, B group using mandibular advancement oral bite and C group using high-flow nasal cannulas. After anesthetic induction, gastric endoscopy will be performed. Oxygenation, end-tidal carbon dioxide, and degree of upper airway obstruction will be evaluated and recorded. Differences between the groups will be evaluated. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04925739 -
Evaluation of the Comfort of a Continuous Positive Airway Pressure Nasal Mask in the Treatment of OSA Syndrome
|
||
| Recruiting |
NCT04179188 -
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome
|
||
| Not yet recruiting |
NCT04131660 -
Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation
|
N/A | |
| Recruiting |
NCT04297163 -
Telemonitoring for the Recuperation of Patients With CPAP
|
N/A | |
| Recruiting |
NCT05661747 -
Dental Appliance to Treat SDB in Children
|
Phase 4 | |
| Not yet recruiting |
NCT06397365 -
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
|
N/A | |
| Completed |
NCT03196583 -
Efficacy of a Novel MAD in OSA
|
N/A | |
| Recruiting |
NCT06462287 -
EFFECT OF A SUBSTANCE P ANTAGONIST ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AND ARTERIAL HYPERTENSION
|
Phase 2 | |
| Not yet recruiting |
NCT05758324 -
Study Evaluating the Effect of a Specific Trace Metal Complex Versus Placebo on the Severity of Apnea in Patients With Obstructive Sleep Apnea Syndrome
|
N/A | |
| Recruiting |
NCT05001464 -
Evaluation of Reliability and Validity of Reflectance Pulse Oximeter in Screening Children With Obstructive Sleep Apnea
|
||
| Active, not recruiting |
NCT04950894 -
Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
|
N/A | |
| Completed |
NCT03398044 -
Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy
|
N/A | |
| Active, not recruiting |
NCT04882020 -
Inflammation and Neurocognitive Damage Markers in Elderly People With Obstructive Sleep Apnea
|
||
| Completed |
NCT05532228 -
Evaluation of the Functional Impact of Adenotonsilectomy
|
||
| Not yet recruiting |
NCT03890549 -
Validation of Downloadable Mobile Snore Applications by Polysomnography (PSG)
|