Clinical Trials Logo

Clinical Trial Summary

The investigators aimed to evaluate the feasibility and safety of using ambient air to protect against thermal injury during RadioFrequency Ablation (RFA) for Renal Cell Carcinoma (RCC) based on data from cases at their institute.


Clinical Trial Description

The incidence of renal cell carcinoma (RCC) has been increasing, particularly among patients >65 years of age. As older individuals are at higher risk for surgical complications, the use of radiofrequency ablation (RFA) for small renal masses (SRM) <4 cm in size, which include T1a tumors,may be a compelling treatment option for elderly patients. However, RFA uses heat to destroy abnormal tissue, with the risk of thermal injury to tissues and organs, including gastric tissue and nerve roots, which are in proximity to the targeted treatment zone. The incidence rate of major complication with RFA, including thermal wounds, has been reported to vary between 3.2% and 5.2%. Different thermal protection methods have been developed to lower the risk of injury to adjacent tissues during ablation, such as air dissection using CO2 injection and hydrodissection using G5% for shielding. Although both of these options are effective, they are expensive. To lower the cost of thermal protection, the investigators have been using ambient air instead of CO2 for air dissection prior to RFA for SRM-RCCs. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03395379
Study type Observational
Source Centre Hospitalier Universitaire de Nice
Contact
Status Completed
Phase N/A
Start date January 11, 2012
Completion date May 15, 2016

See also
  Status Clinical Trial Phase
Recruiting NCT05319132 - Evaluate DF-003 in ex Vivo Assays Using Peripheral Blood Mononuclear Cell From Subjects With ROSAH Syndrome
Completed NCT03766646 - Preoxygenation With Optiflowâ„¢ - the Effect of Speech on Lung Oxygenation. N/A
Completed NCT04995549 - SKin Uncertainties Modeling N/A
Completed NCT05358002 - Comparative Study Between Frontalis Flap Advancement Versus Frontalis Sling Operations in Mangment of Congenital Blepharoptosis N/A
Completed NCT05132608 - Effect of a Social Media-based Health Education Program on Postnatal Care (PNC) Knowledge Among Pregnant Women Using Smartphones in Dhulikhel Hospital N/A
Completed NCT03315949 - Comparison of Bowel Cleansing Efficacy Between Same-day Dose Versus Split Dose Phase 3
Active, not recruiting NCT03079466 - Effect of CPAP Treatment on the Elderly With Mild to Moderate Sleep Apnea N/A
Recruiting NCT06339996 - Male Supplements for Sperm Quality and Aging N/A
Recruiting NCT04931316 - Incidence and Management of Ocular Hypertension Following Deep Anterior Lamellar Keratoplasty
Not yet recruiting NCT06243146 - Titration of Inspired Oxygen to Decrease the Incidence of Postoperative Pulmonary Complications N/A
Completed NCT04299698 - Interaction of Genetic and Environmental Factors for Body Fat Mass Control
Recruiting NCT05478616 - Expression of Endometrium During Window of Implantation
Completed NCT05795998 - Turkish Adaptation of Romantic Relationship Sabotage Scale Validity and Reliability Study
Completed NCT03445442 - Different Surgical Techniques Used for Prolapse Repair in Elderly Patient
Completed NCT03477071 - A 15-year Single Center Experience of Endovascular Treatment of Transplant Renal Artery Stenosis
Completed NCT04102813 - Deep Diaphragmatic Breathing: Neurobiological and Anti-inflammatory Effects N/A
Not yet recruiting NCT03016416 - The Influence of Rhythm, Cognitive Task and Physical Activity on the Cardiac ANS in Chronic Stroke Patients N/A
Not yet recruiting NCT04213612 - DCV in the Treatment of Recurrence and Refractory Childhood Solid Tumors Phase 1
Completed NCT02384837 - Effect of TCFA on Neointimal Coverage After PCI at 9 Months Follow-up N/A
Completed NCT03130283 - Study Design of the Empirical Evaluation of the AISBE Program in Catalonia N/A