Early UVFP Management Based on Neurological Evidences (ION-UVFP) - Preliminary Study

Unilateral Vocal Cord Paralysis Clinical Trial

Official title: Early UVFP Management Based on Neurological Evidences (UVFP = Unilateral Vocal Fold Paralysis) (ION-UVFP) - Preliminary Study

Status Completed

Clinical Trial Summary

The purpose of this preliminary study is to help clarify our hypotheses for the longitudinal study by investigating the relationship between vocal cord paralysis and central auditory processes and thus the interpretation of auditory inputs into the central nervous system.

Clinical Trial Description

A very recent study (Naunheim et al., 2018) shows that paralysis of a vocal cord can affect central auditory processes, which in turn would have a negative impact on motor control capabilities during voice production. This study was conducted in patients who had undergone Type I thyroplasty. To highlight these influences, the authors relied on behavioral tests of auditory perception and vocal production.

The investigators would like in this study, based on a similar and existing population at the Cliniques Universitaires Saint-Luc, to try to understand the changes observed clinically by proposing to perform vocal production tasks (also planned for the longitudinal study) in the MRI. The investigators would like to objectify the differences in the areas involved in the central auditory processes in comparison between patients and control subjects. ;

Related Conditions & MeSH terms

• Auditory Perceptual Disorders
• Central Auditory Processing Disorder
• Language Development Disorders
• Paralysis
• Unilateral Vocal Cord Paralysis
• Vocal Cord Paralysis

• NCT number: NCT03966183
• Study type: Observational [Patient Registry]
• Source: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
• Status: Completed
• Start date: June 15, 2019
• Completion date: September 30, 2023