Undesired Pregnancy Clinical Trial
Official title:
Human Chorionic Gonadotropin (hCG) Trend After Medication Abortion: A Prospective Physiologic Study
This project will be a prospective physiologic study. We will closely follow 60 medication
abortion patients with serial repeat serum hCG and urine semi-quantitative hCG testing. We
plan to recruit patients from two gestational age strata: ≤ 49 days and > 49 days.
Study Objectives:
1. To create a nomogram describing the change in serum hCG values in the first five days
immediately following medication abortion with mifepristone and misoprostol.
Specifically, we will describe the percent serum hCG decline from Day 1 (day of
mifepristone) to Day 3 (day after misoprostol), from Day 1 to Day 5, and from Day 1 to
Day 7-10.
2. To explore whether there is a significant difference in the rate of hCG decline based
on initial gestational age determined by ultrasound and initial serum hCG.
3. To describe the correlation between semi-quantitative urine hCG test results and serum
hCG values to determine how soon after initiating medication abortion the urine test
can detect completed abortion.
We hypothesize that among successful medication abortions, there will be a predictable trend
with at least a 50% drop by Day 3 and 80% drop by Day 5.
n/a
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03888404 -
Attitudes and Decision-making After Pregnancy Testing Study
|
||
| Terminated |
NCT00337792 -
Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)
|
N/A |