Undernutrition Clinical Trial
Official title:
Open Label Prospective Parallel Group Active Comparator Interventional Study to Determine the Efficacy of the Therapeutic Nutritional Intervention in SAM Category Malnourished Children of Satpuda Region.
Present study was designed to evaluate the efficacy of the nutritional intervention, in the SAM (Severe Acute malnutrition)children by monitoring various Anthropometric,Biochemical ,Hormonal and Enzymatic parameters before and after the nutritional intervention treatment.This study was also intended to study possible functional role of gene HRI (heme regulated inhibitor) as a molecular marker for the early detection of iron deficiency anemia in malnourished children similarly present study has also tried to find anthropometric marker and different correlations among study parameters.
In India, child malnutrition is responsible for 22% of the country's burden of disease.
Development of local therapeutic nutritional intervention is highly recommended by WHO.
Present study was designed to evaluate the efficacy of the nutritional intervention, as well
as to study HRI (heme regulated inhibitor) gene expression, to suggest it as a molecular
marker for the early detection of iron deficiency anemia in malnourished children also to
find anthropometric marker and different correlations of study parameters.
105 test and 100 control SAM (Severe Acute malnutrition) children without infection, of 1 to
5 years of age and either sex were enrolled. Test group was given treatment of nutritional
intervention therapy (NIT), providing 2.5 to 3gm Protein and 90-100kcal/kg body Weight/day,
for the three months period. Their Anthropometric, Enzymatic, Biochemical and Hormonal
parameters were measured before and after the NIT. Correlation of serum triglyceride with
weight for height% , as well as correlation of HRI with Mean corpuscular hemoglobin,(MCH) was
studied. Similarly status of Hairs, Skin, oedema, WHO z- score,and BMR was also studied
before and after the NIT.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06084715 -
The INSTITUT Study
|
||
| Recruiting |
NCT05608707 -
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
|
N/A | |
| Completed |
NCT01977950 -
Nutritional Risk and Nutritional Care Practices in the Hospitalized Elderly
|
N/A | |
| Completed |
NCT01197768 -
A Multi-Component Behavioral Nutrition Intervention for Homebound Elderly
|
N/A | |
| Active, not recruiting |
NCT02463565 -
Assessment of Food Intake in Hospitalized Patients
|
N/A | |
| Completed |
NCT05517395 -
The Effectiveness of HBM-based Education Program on Improve Knowledge and Behaviors
|
N/A | |
| Recruiting |
NCT05473312 -
Women Supporting Women to Improve Infant and Child Feeding Practices
|
N/A | |
| Recruiting |
NCT05094024 -
Shelf-Stable MDCF-2 for Children With Undernutrition
|
N/A | |
| Completed |
NCT04105621 -
Westlake Personalized Nutrition and Health Cohort for Drug Addicts
|
||
| Completed |
NCT02213393 -
Cater With Care Effect Study
|
N/A | |
| Completed |
NCT02141256 -
Can Protein Intake be Increased by Offering Protein-enriched Foods and Drinks?
|
N/A | |
| Active, not recruiting |
NCT03450174 -
Effectiveness of Multiple Micro-nutrient Fortified Fudge on Nutritional Status of 3-5 Years of Age Children
|
N/A | |
| Completed |
NCT05574842 -
The Effect of Double Duty Interventions on Double Burden of Malnutrition Among School Adolescents in Ethiopia
|
N/A | |
| Recruiting |
NCT05952479 -
The Comparison of Handgrip Strength, Lean Mass, and Blood Pressure in Primary School Children Aged 8-10 Years Old With Undernutrition and Normal Nutritional Status
|
||
| Completed |
NCT04640389 -
Rural-urban Disparities in the Nutritional Status of Younger Adolescents in Tanzania.
|
||
| Completed |
NCT03378141 -
Maternal Nutrition Interventions in Uttar Pradesh, India
|
N/A | |
| Completed |
NCT03211845 -
Feasibility of Nutritional Telemonitoring in Elderly Home Care Patients
|
N/A | |
| Completed |
NCT02496247 -
Canned Herring for Prevention of Childhood Malnutrition During the Early Rainy Season in Rural Guinea-Bissau
|
N/A | |
| Completed |
NCT02476110 -
The ONSHUG Survey : A Quality Care Programme
|
N/A | |
| Completed |
NCT02656186 -
Supplementation With Nutrients Modulating IGF-1 and Cytokines in Elderly People at Risk of Undernutrition
|
Phase 3 |