Uncomplicated Malaria Clinical Trial
Artemisinin combination therapies (ACT) are currently recommended for malaria treatment. Artemether-lumefantrine(A-L) and Artesunate+amodiaquine (A+A) have been the most commonly adopted of the recommended ACT regimens. In Ghana, A+A is the current first-line antimalarial treatment in Ghana, but there has been 1 efficacy report of this regimen in Ghana till date. Moreover, the safety of repeated treatments with ACT has been little studied. This study aims to evaluate the efficacy of A+A vs. A-L, as well as the safety of repeated treatments of these regimens in a longitudinal trial in which recruited children will be followed up for 1 year.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT00540202 -
Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children
|
Phase 4 | |
| Completed |
NCT02787070 -
A Randomized Controlled Trial on Malaria Primaquine Treatment in Timika, Indonesia (TRIPI)
|
Phase 4 | |
| Completed |
NCT01213433 -
Amodiaquine+Artesunate for Uncomplicated Malaria Treatment
|
Phase 4 | |
| Completed |
NCT05192265 -
Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine
|
Phase 2/Phase 3 | |
| Completed |
NCT04767191 -
Malaria Therapeutic Efficacy Study (TES) Kenya
|
Phase 4 | |
| Completed |
NCT04767217 -
Malaria Therapeutic Efficacy Study, Rwanda
|
Phase 4 | |
| Completed |
NCT06036030 -
Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua
|
Phase 2 | |
| Recruiting |
NCT06064591 -
Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX
|
||
| Completed |
NCT06300970 -
Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia
|
Phase 4 | |
| Completed |
NCT00845533 -
Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina Faso
|
Phase 4 | |
| Completed |
NCT03387631 -
Efficacy And Safety Of AL For The Treatment Of Uncomplicated Falciparum Malaria In Mainland Tanzania
|
N/A | |
| Completed |
NCT00868465 -
Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy (TRANSACT)
|
N/A | |
| Completed |
NCT00460369 -
Treatment of Uncomplicated Malaria in Benin
|
N/A | |
| Completed |
NCT00459615 -
Phase II Dose Ranging Study of Artesunate
|
Phase 2 | |
| Not yet recruiting |
NCT05911828 -
A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carriers
|
Phase 1 |