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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06321848
Other study ID # DUCGM2426
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date April 22, 2024
Est. completion date April 2026

Study information

Verified date May 2024
Source Hanoi Medical University
Contact Duc Tran, MD
Phone +84983817388
Email ductran.hmu@gmail.com
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

Postextubation distress is detrimental to the prognosis of critically ill patients with successful spontaneous breathing trial. Failure to wean is known to be connected with heart, lung, and diaphragm problems. The aim of this study was to investigate how a composite model comprising diaphragm, lung, and heart ultrasonography indications could predict the weaning outcome. Methods: Ultrasonic features of the diaphragm, heart, and lungs are going to be collected along with clinical data about the patients. Either the successful weaning group or the failed weaning group is going to comprised the patients. Multivariate logistic regression analysis is going to be used to identify the variables that may be associated with the likelihood of weaning failure. A multiindicator combination model is going to be developed to increase the predictive accuracy after the possible indicators' accuracy in foretelling the weaning outcome was assessed.


Description:

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Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
Vietnam Hanoi Medical University Hospital Hanoi

Sponsors (1)

Lead Sponsor Collaborator
Hanoi Medical University

Country where clinical trial is conducted

Vietnam, 

Outcome

Type Measure Description Time frame Safety issue
Primary The ventilator weaning outcome The outcome of weaning ventilation process (successful or failure) after 48 hours of extubation
Secondary The hospital length of stay The time between hospital admission and discharge Approximately 5-15 days postextubation
Secondary The ICU length of stay The time between ICU admission and discharge Approximately 2-15 days postextubation
Secondary The duration of mechanical ventilation The time from the start of mechanical ventilation to extubation Daily assessment of requirement of mechanical ventilation from the time of intubation until the date of weaning mechanical ventilation, up to 12 months
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