Evaluation of the Vulnerable Carotid Atherosclerotic Plaque: A Clinical Multicenter Study

Ultrasound Clinical Trial

Official title:

Evaluation of the Vulnerable Carotid Atherosclerotic Plaque: A Clinical Multicenter Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05849909
• Other study ID #: 2023-0402
• Status: Recruiting
• Start date: April 18, 2023
• Est. completion date: April 18, 2024

Study information

• Verified date: April 2023
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Evaluation of carotid plaque vulnerability based on ultrasound imaging features， proteomics and metabolomics: a clinical multicenter study

Description:

Carotid artery plaque tissue specimen for proteomics. Blood were collect for metabolomics.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 57
• Est. completion date: April 18, 2024
• Est. primary completion date: April 20, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

1. Patients who meet the CEA surgical indications;

2. Age>18 years old;

3. Patients who sign informed consent forms

Exclusion Criteria:

1. Those with severe calcification of plaques and obvious acoustic shadows, and poor image quality;

2. Contraindications to ultrasound contrast, such as those who are allergic to contrast agents;

3. Intracardiac right to left shunt;

Related Conditions & MeSH terms

• Plaque, Atherosclerotic
• Ultrasound

Locations

Country	Name	City	State
China	Department of Ultrasound, Second Affiliated Hospital, School of Medicine, Zhejiang University	Hangzhou	Zhejiang

Sponsors (2)

Lead Sponsor	Collaborator
huang pintong	Second Affiliated Hospital, School of Medicine, Zhejiang University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	ultrasound	B mode	2023.05