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Ulnar Neuropathies clinical trials

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NCT ID: NCT03737916 Completed - Ulnar Neuropathies Clinical Trials

The Effect of Perineural Dextrose Injection in Patients With Ulnar Neuropathy at the Elbow

Start date: November 18, 2018
Phase: N/A
Study type: Interventional

Ulnar neuropathy at the elbow (UNE) is the second most common neuropathy and occurs after recurrent or elongated elbow flexion. Diagnosis of UNE depends on clinical symptoms, physical examination, and electrophysiological findings. Imaging methods such as ultrasonography (USG) and magnetic resonance imaging show cross-sectional area and echogenicity of ulnar nerve and give information about to surrounding structures around the ulnar nerve. In mild and moderate cases, conservative treatments are administered up to 6 months, who do not benefit from conservative treatment are referred to surgery. There are not many options for conservative treatment. Activity modification, nerve gliding exercises and night splints are conservative treatment methods. Steroid injection is no longer recommended. Perineural dextrose injection is applied in tendinopathies and entrapment neuropathies (especially carpal tunnel syndrome). In the literature, there is no study showing effect of perineural dextrose injection in patients with UNE. The investigators design a randomized, double-blind, controlled trail to evaluate the effect after ultrasound-guided perineural injection with 5% dextrose in patients with UNE.

NCT ID: NCT03651609 Recruiting - Clinical trials for Peripheral Nervous System Diseases

Treatment for Ulnar Neuropathy at the Elbow

UNETREAT
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate utility and appropriateness of treatment interventions taking into account the presumed mechanisms of two main varieties of ulnar neuropathy at the elbow (UNE). The investigators hypothesize that in patients with UNE under the humeroulnar aponeurosis (HUA) surgical HUA release (simple decompression) is superior to conservative treatment. By contrast, in patients with UNE at the retroepicondylar (RTC) groove surgical HUA release (simple decompression) should not be superior to conservative treatment.

NCT ID: NCT03209947 Completed - Ulnar Neuropathies Clinical Trials

ULnar Nerve ECHographic Observation (ULNECHO)

ULNECHO
Start date: September 22, 2017
Phase: N/A
Study type: Interventional

There is currently no consensus on the normal ultrasound surface of the ulnar nerve at the elbow. The goal of this study is to study the ulnar nerve surface at the elbow in a population of asymptomatic subjects

NCT ID: NCT02986906 Completed - Clinical trials for Ulnar Neuropathy at Elbow

Perineural Injection Therapy for Ulnar Neuropathy at Elbow

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Ulnar neuropathy at elbow (UNE) is the second common peripheral entrapment neuropathy. Although many conservative managements of UNE, the effectiveness of these methods are unsatisfied especial the moderate degree of UNE. Recently, ultrasound-guided perineural injection therapy (PIT) with 5% dextrose is progressively applicated for clinical treatment for entrapment neuropathy. However, current studies have not proved the effects of PIT on peripheral neuropathy because these studies enrolled small number of patients and lacked controlled design. We design a randomized, double-blind, controlled trail to assess the effect after ultrasound-guided PIT with 5% dextrose in patients with mild and moderate UNE.

NCT ID: NCT02533024 Completed - Ulnar Neuropathy Clinical Trials

Preoperative Prevalence of Ulnar Neuropathy and Changes in Ulnar Nerve Latency During Surgery

Start date: August 2015
Phase: N/A
Study type: Interventional

This study is to investigate the incidence of undiagnosed ulnar neuropathy in patients undergoing surgery. The investigators hope to determine if patients with ulnar neuropathy have changes in nerve conduction latency during surgery.

NCT ID: NCT02281656 Completed - Clinical trials for Severe Compressive Ulnar Nerve Neuropathy (McGowan Grade III)

Prospective Evaluation of Reverse End to Side Anterior Interosseous Nerve to Ulnar Nerve Transfer for Severe Compressive Ulnar Neuropathy at the Elbow

Start date: January 2015
Phase: Phase 3
Study type: Interventional

Ulnar nerve compression at the elbow is a common problem and can significantly affect hand function in severe cases. The current, standard treatment is Ulnar nerve decompression with or without transposition (moving the ulnar nerve to a site where there is less compression). In severe compression, the clinical results after this surgery are typically poor. Distal transfers of functioning nerves (at the level of the wrist) to the compressed ulnar nerve (anterior interosseous nerve to ulnar motor fascicles) have been suggested to "supercharge" or augment hand muscles while nerve axons regenerate from the level of the elbow after decompression/transposition. In fact, this treatment is becoming widely adopted without clear evidence that it changes outcomes. The investigators propose to prospectively compare the effectiveness of ulnar nerve decompression/transposition versus decompression/transposition and distal nerve transfer.

NCT ID: NCT01394822 Completed - Clinical trials for Carpal Tunnel Syndrome

Neuromuscular Ultrasound for Focal Neuropathies

Start date: September 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine if a new diagnostic technique, called neuromuscular ultrasound, can improve our ability to diagnose focal nerve disease.

NCT ID: NCT01215760 Completed - Clinical trials for Median Nerve Disease

Sensory Reeducation in Peripheral Nerve Injuries of Hand

HandtherRCT
Start date: March 2009
Phase: N/A
Study type: Interventional

Objectives: To develop a protocol for early treatment using sensory reeducation through the mirror after surgical reconstruction of the median nerve and / or ulnar hand, and its comparison with the evolution of the return of skin sensitivity after a not early rehabilitation which will be conducted by physiotherapists, with blinding of the evaluators.