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Type 2 Diabetes Mellitus (T2DM) clinical trials

View clinical trials related to Type 2 Diabetes Mellitus (T2DM).

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NCT ID: NCT01755494 Completed - Clinical trials for Type 2 Diabetes Mellitus(T2DM)

A Bioequivalence Study of the Fixed Dose Combinations of Saxagliptin/Metformin XR Relative to Co-Administration

SAXA
Start date: February 2013
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to assess the pharmacokinetic parameters of saxagliptin and metformin in healthy male Chinese subjects.

NCT ID: NCT01407003 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Assessment of LIK066 in Healthy Subjects and in Patients With Type 2 Diabetes Mellitus (T2DM)

Start date: June 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess safety, tolerability, and effect of LIK066 on blood glucose in healthy subjects and in patients with T2DM.

NCT ID: NCT01131182 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)

Start date: June 13, 2010
Phase: Phase 4
Study type: Interventional

This study will examine whether the incidence of hypoglycemia in patients fasting for Ramadan is lower when treated with sitagliptin as compared to sulfonylurea treatment.

NCT ID: NCT01127308 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038)

Start date: June 2010
Phase: Phase 1
Study type: Interventional

This is single dose study of radiolabeled [14C]-ertugliflozin (PF04971729, MK-8835) in healthy male volunteers to study the absorption, distribution, metabolism and elimination of ertugliflozin.

NCT ID: NCT01002807 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State

Start date: November 2009
Phase: Phase 1
Study type: Interventional

To assess the relative bioavailability of dapagliflozin and metformin from the two FDC formulations, comprised of 10 mg dapagliflozin and 1000 mg metformin XR, relative to coadministration of a dapagliflozin 10 mg tablet and 2 x 500 mg Glucophage® XR tablets, in healthy subjects in a fasted state.

NCT ID: NCT00829660 Completed - Clinical trials for Acute Coronary Syndrome

Acarbose Cardiovascular Evaluation Trial

ACE
Start date: February 17, 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether acarbose therapy can reduce cardiovascular-related morbidity and mortality in patients with impaired glucose tolerance (IGT) who have established coronary heart disease (CHD) or acute coronary syndrome (ACS). A secondary objective of the study is to determine if acarbose therapy can prevent or delay transition to type 2 diabetes mellitus (T2DM) in this patient population.

NCT ID: NCT00704132 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Sitagliptin Mechanism of Action Study in Patients With Type 2 Diabetes Mellitus (0431-059)

Start date: February 2007
Phase: Phase 1
Study type: Interventional

A clinical study to determine the safety, efficacy and the way sitagliptin works in patients with Type 2 Diabetes Mellitus who have inadequate glycemic (blood sugar) control.

NCT ID: NCT00511108 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Sitagliptin and Pioglitazone Mechanism of Action Study in Type 2 Diabetes Mellitus (0431-061)

Start date: July 2007
Phase: Phase 1
Study type: Interventional

A clinical study to determine the safety, efficacy and mechanism of action of sitagliptin alone and in combination with pioglitazone, in patients with type 2 diabetes mellitus who have inadequate glycemic (blood sugar) control.

NCT ID: NCT00337610 Completed - Clinical trials for Type 2 Diabetes Mellitus (T2DM)

Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus

Start date: June 2006
Phase: Phase 3
Study type: Interventional

A clinical study to determine the safety and efficacy of sitagliptin in patients with Type 2 Diabetes Mellitus who have inadequate glycemic (blood sugar) control on metformin therapy.