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NCT01552811 Clinical Trial

Studies of Pancreatic Islet Mass by Positron Emission Tomography (PET)

Type 1 Diabetes Clinical Trial

Official title:
Open Study to Investigate Pancreatic Islet Mass by Positron Emission Tomography Using the Tracer [11C]5-hydroxytryptophane

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01552811
Other study ID # AS Dnr2011/439
Secondary ID
Status Completed
Phase N/A
First received March 9, 2012
Last updated February 4, 2014
Start date March 2012
Est. completion date March 2013

Study information
Verified date February 2014
Source Uppsala University Hospital
Contact n/a
Is FDA regulated No
Health authority Sweden: Regional Ethical Review Board
Study type Observational

Clinical Trial Summary

This study investigates the hypothesis that differences in beta-cell mass in patients with diabetes and healthy individuals can be monitored by the positron emission tomography (PET) tracer [11C]5-hydroxytryptophane.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date March 2013
Est. primary completion date March 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Adult patients with type 1 diabetes

- Adult, healthy controls

Exclusion Criteria:

- Pregnancy

- Impaired renal function

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Sweden Uppsala University Hospital Uppsala

Sponsors (1)
Lead Sponsor Collaborator
Uppsala University Hospital

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary Difference in pancreatic uptake of % injected dose (ID) [11]5-hydroxy tryptophan between healthy volunteers and patients with long-standing type 1 diabetes To be measured at Positron emission tomography investigation for all study persons. No
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