Tumor Clinical Trial
Official title:
Radiation Therapy and Cardiac Biomarkers
The goal of this clinical research study is to learn if the radiation that you are receiving will result in an increase in certain proteins produced by the heart called cardiac biomarkers.
Cardiac Biomarkers:
Cardiac biomarkers are proteins made by the heart. When cardiac biomarkers are above normal
levels, there may be damage to the heart. The relationship between cardiac biomarkers and
radiation therapy has not been well studied. Learning more about this relationship may lead
to better ways to check the heart during radiation therapy. How cardiac biomarkers can play a
role in predicting future heart problems during radiation therapy will also be studied.
Study Tests:
If you agree to take part in this study, blood (about 1 teaspoon) will be drawn to measure
certain cardiac biomarkers up to 2 days before radiation therapy, following the first
treatment of radiation, within 2 days of finishing radiation therapy, and about 1 to 2 months
after completion of radiation therapy. Once the blood testing is completed, any leftover
blood samples will be destroyed.
You will also have electrocardiograms (ECGs -- tests that measure the electrical activity of
the heart) at the same time points as the blood draws.
Length of Study:
You will be off study after the last blood draw and ECG.
This is an investigational study. Up to 30 patients will be enrolled in this study. All will
be enrolled at M. D. Anderson.
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