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Tropical Disease clinical trials

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NCT ID: NCT06070116 Enrolling by invitation - Onchocerciasis Clinical Trials

Safety and Efficacy of Novel Combination Regimens for Treatment of Onchocerciasis

Start date: April 5, 2024
Phase: Phase 2
Study type: Interventional

This study will investigate the safety and effectiveness of combination regimens in persons with onchocerciasis when it is administered after pre-treatment with ivermectin to clear or greatly reduce microfilariae from the skin and eyes.

NCT ID: NCT04706819 Not yet recruiting - Neurocysticercosis Clinical Trials

Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study

Start date: January 15, 2021
Phase:
Study type: Observational [Patient Registry]

Neurocysticercosis(NCC) is the commonest parasitic infection of the central nervous system. It is the commonest cause of focal seizures in India. It can also present with headaches, movement disorders, stroke, cognitive decline and multitude of complications depending on its location. Parenchymal NCC is more common than extraparenchymal NCC. There is considerable variation in the treatment practices including administration of anti-helminthic agents and corticosteroids. Extra-parenchymal NCC is rare and can occur in the subarachnoid space or intraventricularly. Extra-parenchymal NCC is managed surgically in several instances. There is scant literature on the long term follow up of this condition. This registry will enable collection of data on the clinical, laboratory and imaging features, treatment trends and long term outcomes of both parenchymal and extra-parenchymal neurocysticercosis.

NCT ID: NCT03912246 Completed - Infectious Disease Clinical Trials

Collection of Human Biological Samples for the Development and Validation of New Methods of Diagnosis and for the Realization of Expertises Diagnostics in the Field of Infectious Diseases and Tropical

Diagmicoll
Start date: April 27, 2009
Phase: N/A
Study type: Interventional

Direct constitution of collections from various samples taken on a prospective cohort of healthy volunteers, to prepare human biological samples of known characteristics (biochemical and serological in particular) and quality controlled.

NCT ID: NCT03078894 Recruiting - Tropical Disease Clinical Trials

A Pilot Study Examining for the Presence of Fecal Coliforms and Tropical Diseases in Peru

Start date: March 17, 2017
Phase: N/A
Study type: Observational

Tropical diseases are continuously on the rise throughout the world as they are spreading and manifesting in various locations globally. The more prominent vector tends to be the mosquito after it bites a previously infected host. The viruses of Zika, Chikungunya, and Dengue are some of the tropical diseases that are affecting large populations and expanding rapidly. Developing countries are at the highest risk because of the lack of preventive methods that are customarily demonstrated in developed countries. Sanitation issues complicate the problem as contaminated wastewater is ideal for mosquitos to lay eggs. In addition, the organic material in the wastewater serve as food for larvae. The purpose of this study is to test bodies of waters in Peru and examine if contaminated water is a contributing factor in the proportion of the population infected with Zika, Chikanguyna or Dengue.