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Tricuspid Regurgitation clinical trials

View clinical trials related to Tricuspid Regurgitation.

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NCT ID: NCT02831270 Completed - Clinical trials for Mitral Regurgitation

Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery

Start date: December 2011
Phase: N/A
Study type: Observational

Serum-creatinine level (s-Cr) is an important factor for predicting perioperative patient's outcome regarding acute kidney injury. Although cardiopulmonary bypass (CPB), an essential procedure for cardiac surgery, dilutes patient's blood components, possible impact of applying acute normovolemic hemodilution (ANH) and CPB on s-Cr has not been well investigated. In patients undergoing cardiac surgery employing moderate hypothermic CPB (age 20-71 years, n=32), ANH will be randomly applied to 15 patients (Group-ANH) but not in 17 patients (Group-C) before initiating CPB. For ANH procedure consisting of 5 ml/kg of blood salvage and administering 5 ml/kg of balanced hydroxyethyl starch (HES) 130/0.4 for 15 min will be started at 30 min after anesthesia induction and before CPB application for surgery. In both groups, moderate hypothermic CPB will be initiated by using 1600-1800 ml of bloodless priming solution. The changes of hematocrit (Hct), Na+, K+, HCO3-, Ca2+, osmolarity, s-Cr will be determined before ANH (T1), after the first ANH of 2.5 ml/kg (T2), and after the second ANH of 2.5 ml/kg (T3), 30 sec and 60 sec after the initiation of CPB (T4, T5), immediately and 1 hour after the weaning from CPB (T6, T7) and at the end of surgery (T8). S-Cr will be determined by using a point-of-care test device (StatSensor™ Creatinine, Nova Biomedical, USA).

NCT ID: NCT02675244 Completed - Clinical trials for Tricuspid Regurgitation

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Start date: May 26, 2016
Phase: N/A
Study type: Interventional

The purpose of the research is to determine whether repairing a tricuspid valve (TV) in patients with mild to moderate tricuspid regurgitation (TR), at the time of planned mitral valve surgery (MVS), would improve the heart health of those who receive it compared to those who do not. At this point, the medical community is split in their opinion on whether surgeons should routinely repair mild to moderate TR in patients who are undergoing planned mitral valve surgery, and this study will answer this question.

NCT ID: NCT02644616 Completed - Clinical trials for Tricuspid Regurgitation

The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The investigators research the early improvement of fluid retention and mid-term prognosis through the administration of tolvaptan for the patient with tricuspid regurgitation and right heart failure after left heart valves replacement.

NCT ID: NCT02502448 Completed - Clinical trials for Mitral Regurgitation

Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery

Start date: January 2016
Phase: N/A
Study type: Interventional

Impact of acute normovolemic hemodilution (ANH) using hydroxyethyl starch before initiating cardiopulmonary bypass (CPB) on whole blood viscoelastic profile after CPB has not been well established. Patients undergoing cardiac surgery employing moderate hypothermic CPB (n=40) are randomly allocated into one of two groups: in Group-ANH(n=20), ANH is applied by using a balanced hydroxyethyl starch (HES 130/0.6); and in Group-C, ANH is not applied. After weaning from CPB, intergroup differences of INTEM, EXTEM, FIBTEM and APTEM profiles are analyzed. As a primary outcome, inter-group difference between maxiaml clot firmness of EXTEM will be determined at 10 min after ANH in Group-ANH and that at control.

NCT ID: NCT02098200 Completed - Clinical trials for Tricuspid Regurgitation

Percutaneous Treatment of Tricuspid Valve Regurgitation With the TriCinch System™

PREVENT
Start date: June 2013
Phase: Phase 1
Study type: Interventional

The TriCinch System™ is intended for percutaneous treatment of tricuspid regurgitation. It is a percutaneous catheter-based device designed for tricuspid valve repair in order to decrease effective cross-sectional area and relieve symptoms in patients with tricuspid valve regurgitation.

NCT ID: NCT01502462 Completed - Clinical trials for Tricuspid Regurgitation

Prospective Registry of Patients With Isolated Severe Tricuspid Regurgitation

Start date: February 2012
Phase:
Study type: Observational

Prospective registry for patients with severe isolated tricuspid regurgitation (TR) without significant left-sided valvular or myocardial diseases. Aim: To evaluate clinical course and prognostic factors of patients with severe isolated TR.

NCT ID: NCT01203137 Completed - Clinical trials for Tricuspid Regurgitation

Prognostic Value of Early Postoperative Right Ventricular Systolic Function in Patients With Isolated Severe Tricuspid Regurgitation

Start date: January 2009
Phase: N/A
Study type: Observational

Preoperative right ventricular end-systolic area (RV-ESA) and hemoglobin level were suggested as independent prognosticator for predicting long-term prognosis in patients with isolated severe TR undergoing corrective surgery We attempted to explore whether early postoperative echocardiography provides additional prognostic information on top of preoperative clinical and echocardiographic variables.

NCT ID: NCT01093001 Completed - Clinical trials for Left Ventricular Dysfunction

Tricuspid Regurgitation Study

Start date: May 2010
Phase: Phase 4
Study type: Interventional

The effect of cardiac pacing leads on tricuspid regurgitation is unclear. This study will determine whether using a smaller diameter leads and an alternate position in the ventricle, the proximal septum, will reduce tricuspid regurgitation than larger leads placed in the apex.

NCT ID: NCT00665301 Completed - Clinical trials for Congestive Heart Failure

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

Start date: March 2008
Phase: N/A
Study type: Observational

The purpose of this study is to compare cardiac output results obtained using the thermodilution push technique with the Pulmonary Arterial Catheter (PAC) to the predicted cardiac output results obtained from the non-invasive FloWave™ 1000 device.