Tremor Clinical Trial
Official title:
The Development of a System for the Measurement of Tremor
NCT number | NCT06386822 |
Other study ID # | 23-1562H |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | August 1, 2023 |
Est. completion date | December 2024 |
The goal of this clinical trial is to develop a system which can be used to measure movements in people with Essential Tremor (with or without dystonia). The main questions it aims to answer are: - Can individuals with Essential Tremor be distingushed from individuals without tremor using Virtual Reality (VR) - Can the current Essential Tremor Assessment Scale (the TETRAS) be reproduced in VR - Can Essential Tremor be quantified using a measurement system - Can Dystonia be quantified using a measurement system. Participants will don the equipment used to measure their tremor and replicate a series of standardised movements to measure their tremor, in and out of the VR platform. The assessment will take no longer than an hour.
Status | Recruiting |
Enrollment | 120 |
Est. completion date | December 2024 |
Est. primary completion date | December 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Control participants: Inclusion Criteria: - Aged 18 to 80 years - Able to provide informed consent for self - Able to comply with all study procedures Exclusion Criteria: - Any neurological disorder - Any other non-neurological cause of tremor e.g. medication induced Essential tremor participants: Inclusion Criteria: - Aged 18 to 80 years - Able to provide informed consent for self - Clinical diagnosis of ET or ET plus syndrome - Able to comply with all study procedures Exclusion Criteria: - Tremor other than ET (e.g. parkinsonian, functional tremor) - Presence of other movement disorder - For DBS participants: unwilling or unable to turn off and on their own stimulator for the duration of the study. |
Country | Name | City | State |
---|---|---|---|
Australia | The Royal Victorian Eye and Ear Hospital | East Melbourne | Victoria |
Lead Sponsor | Collaborator |
---|---|
The Bionics Institute of Australia |
Australia,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To quantify Essential Tremor and dystonia using a measurement system | Using commercially available Virtual Reality (VR) equipment and a commercially available Inertial Measurement Unit (IMU), the presence of the tremor and dystonia in participants with Essential Tremor will be measured and their severity rated. | At enrolment. This study is a single assessment conducted at one time point. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02427646 -
Kinematic-guided BoNT-A Treatment for ET and PD Tremor
|
Phase 2 | |
Completed |
NCT01018485 -
The Efficacy of Botulinum Toxin in Disabling Multiple Sclerosis (MS) Tremor
|
Phase 3 | |
Completed |
NCT02087046 -
Deep Brain Stimulation (DBS) for the Suppression of Tremor
|
N/A | |
Recruiting |
NCT05413291 -
Natural History Protocol for Movement Disorders
|
||
Recruiting |
NCT04654429 -
Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?
|
Phase 4 | |
Recruiting |
NCT04825119 -
Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen
|
||
Recruiting |
NCT05150106 -
Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor
|
||
Completed |
NCT05152836 -
The Effect of Vibrotactile Stimulation on Parkinson's Tremor
|
N/A | |
Recruiting |
NCT04071847 -
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
|
||
Completed |
NCT02046863 -
Pilot Study for Automated Deep Brain Stimulation Programming
|
N/A | |
Not yet recruiting |
NCT06378619 -
Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach
|
||
Completed |
NCT03300193 -
The Effect of Lesion Characteristics in MRgFUS on Tremor in Essential Tremor and Parkinson's Disease
|
N/A | |
Completed |
NCT01932463 -
ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) for Treatment of Tremor
|
N/A | |
Recruiting |
NCT05216770 -
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
|
Early Phase 1 | |
Not yet recruiting |
NCT06174948 -
The Use of the CUE1 in People With Parkinson's Disease and Related Disorders
|
N/A | |
Completed |
NCT01093027 -
Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor
|
N/A | |
Completed |
NCT00001667 -
Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases
|
N/A | |
Completed |
NCT00001324 -
PET Scan to Study Brain Control of Human Movement
|
||
Completed |
NCT04299087 -
Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor
|
N/A | |
Recruiting |
NCT05150093 -
Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
|
N/A |