Stem Cells for Uremic Calciphylaxis Patients

Status Active, not recruiting

Clinical Trial Summary

Treatment for Uremic Calciphylaxis Patients with Human Amniotic Mesenchymal Stem Cells

Clinical Trial Description

Calciphylaxis is a rare, devastating disorder causing excruciatingly painful ischemic skin lesions. Sepsis due to the infection of ulcerated wounds is a common cause of death. To date, practical therapies typically include wound care, pain management, anti-infection and aggressive treatment of predisposing conditions. Drugs such as sodium thiosulfate, bisphosphonate, and cinacalcet are also suggested. However, it's still a lethal disease with 1-year mortality up to 80% for dialysis patients. Here the investigators plan to treat uremic calciphylaxis patients with human amniotic mesenchymal stem cells (hAMSCs). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04592640
Study type	Interventional
Source	The First Affiliated Hospital with Nanjing Medical University
Contact
Status	Active, not recruiting
Phase	N/A
Start date	September 17, 2018
Completion date	September 17, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06386172` - Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm	N/A
Recruiting	`NCT04910867` - APOL1 Genetic Testing Program for Living Donors	N/A
Completed	`NCT03434145` - Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases	N/A
Recruiting	`NCT04984226` - Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD	Phase 2
Active, not recruiting	`NCT05887817` - Effects of Finerenone on Vascular Stiffness and Cardiorenal Biomarkers in T2D and CKD (FIVE-STAR)	Phase 4
Recruiting	`NCT05318196` - Molecular Prediction of Development, Progression or Complications of Kidney, Immune or Transplantation-related Diseases
Terminated	`NCT05022329` - COVID-19 Vaccine Boosters in Patients With CKD	Phase 2/Phase 3
Not yet recruiting	`NCT04925661` - HEC53856 Phase Ib Study in Patients With Non-dialysis Renal Anemia	Phase 1
Recruiting	`NCT04961164` - Resistant Starch Prebiotic Effects in Chronic Kidney Disease	N/A
Completed	`NCT05015647` - Low Protein Diet in CKD Patients at Risk of Malnutrition	N/A
Completed	`NCT03426787` - Helping Empower Liver and Kidney Patients	N/A
Recruiting	`NCT06094231` - Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study	N/A
Completed	`NCT04363554` - The Kidneys Ability to Concentrate and Dilute Urine in Patients With Autosomal Dominant Polycystic Kidney Disease	N/A
Recruiting	`NCT04831021` - Pre- or Per-dialytic Physical Exercise : a Cardioprotective Role?	N/A
Terminated	`NCT04877847` - Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury	N/A
Recruiting	`NCT04422652` - Combination of Novel Therapies for CKD Comorbid Depression	Phase 2
Completed	`NCT05055362` - Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study	N/A
Not yet recruiting	`NCT06330480` - Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease	N/A
Recruiting	`NCT03176862` - Left Ventricular Fibrosis in Chronic Kidney Disease	N/A
Terminated	`NCT02539680` - Intestinal Phosphate Transporter Expression in CKD Patients	N/A