Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy

Status Completed

Clinical Trial Summary

Application of multi-center, prospective study on the severity of postoperative cholangitis biliary atresia classification, according to the degree of cholangitis targeted therapy, to improve the therapeutic effect of postoperative cholangitis biliary atresia, decrease the overuse of antibiotics related complications.

Clinical Trial Description

Cholangitis patients post-kasai Portoenterostomy were grouped by cholangitis severity score, according to the severity was divided into mild, moderate, severe cholangitis, all levels of cholangitis patients were divided into subgroups by age and post-kasai Portoenterostomy jaundice matching design of experiment, then they were randomly divided into control group and experimental group, and all the control group unified antibiotic treatment, the experimental group was graded antibiotic treatment according to the severity cholangitis, after three days treatment，evaluate each treatment effect, average hospitalization days, the average hospitalization expenses, antimicrobial drug use strength to evaluate the therapeutic effect of postoperative cholangitis biliary atresia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04370145
Study type	Interventional
Source	Tongji Hospital
Contact
Status	Completed
Phase	Phase 4
Start date	May 1, 2021
Completion date	April 1, 2022

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