Trauma Clinical Trial - Beta Blockade in Critical Injury

Status Terminated

Clinical Trial Summary

Critically injured patients endure a period of hypermetabolism/catabolism after being resuscitated. The metabolic cost of this may be measured in loss of lean body mass, poor wound healing, susceptibility to infection and long hospital stays. While there have been some data to suggest that hypermetabolism can be ameliorated in burn patients by beta blockade, to our knowledge, a prospective trial in trauma patients has not yet been done. Our hypothesis is that nonselective beta blockade will reduce catabolism, improve glucose control, blunt loss of lean body mass, decrease infections and improve outcome in a cohort of critically injured patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Trauma

Clinical Trial Details

NCT number	NCT00356187
Study type	Interventional
Source	Denver Health and Hospital Authority
Contact
Status	Terminated
Phase	Phase 2
Start date	February 15, 2006
Completion date	January 31, 2009

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