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Trauma, Spinal Cord clinical trials

View clinical trials related to Trauma, Spinal Cord.

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NCT ID: NCT05244408 Recruiting - Clinical trials for Spinal Cord Injuries

"SCRIBBLE" Spinal Cord Injury Blood Biomarker Longitudinal Evaluation

SCRIBBLE
Start date: March 17, 2023
Phase:
Study type: Observational

Prospective, single center study designed to assess blood biomarkers for classifying injury severity and predict neurologic recovery in traumatic spinal cord injured (SCI) patients. Study will also establish the accuracy of point to care devices for SCI blood biomarkers and support the biospecimen collection for the International Spinal Cord Injury Biobank (ISCIB).

NCT ID: NCT03253952 Recruiting - SPINAL Fracture Clinical Trials

A Study of Autonomic Dynamic Dysfunction to Predict Infections After Spinal Cord Injury.

Start date: September 29, 2017
Phase:
Study type: Observational

The study is designed to investigate whether autonomic shifts (dysautonomia, sympatho-vagal instability) that develop after SCI have value in predicting SCI-associated infections (SCI-AI). SCI-AI impair outcomes by (1) reducing the intrinsic neurological recovery potential and (2) increasing mortality. Heart Rate Variability (HRV) data will be tracked in both the time and frequency domains to discriminate between the relative contribution of sympathetic and parasympathetic innervation to changes in HRV. The ability to predict infections will enable novel treatments thereby reducing infection-associated mortality and improving neurological and functional outcomes.