Evaluation of Right Ventricular Systolic Function by TAPSE Parameter From Subcostal View

Transthoracic Echocardiography Clinical Trial

Official title:

Echocardiographic Evaluation of Right Ventricular Systolic Function by TAPSE Parameter Measured From Subcostal View Using Anatomical M-mode - Validation Clinical Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04490538
• Other study ID #: 284/34
• Status: Recruiting
• Start date: July 27, 2020
• Est. completion date: October 31, 2020

Study information

• Verified date: August 2020
• Source: Emergency Medical Service of the Central Bohemian Region, Czech Republic
• Contact: Roman Skulec, MD, PhD
• Phone: 00420777577497
• Email: skulec[@]email.cz
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to validate a new echocardiographic parameter evaluating right ventricular function.

Description:

The key conventional echocardiographic parameter evaluating right ventricular systolic function is the tricuspid annular plane systolic excursion (TAPSE). It is measured in apical four chamber view by conventional M-mode imaging. Other echocardiographic parameters of right ventricular systolic function (Fractional Area Change; Tricuspid Lateral Annular Systolic Velocity; Right Ventricular Index of Myocardial Performance) are evaluated in apical four chamber view as well. However, this view might not be clearly visible in the clinical setting of critical illness and subcostal view is often preferred for its higher quality. Unfortunately, conventional M-mode can not be used for measurement in this view but anatomical M-mode imaging can. Therefore, the investigators decided to evaluate whether TAPSE measured in subcostal view by anatomical M-mode (sTAPSE) correlates with conventional TAPSE and whether reliably reflects systolic right ventricular function.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: October 31, 2020
• Est. primary completion date: September 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Inpatients

• All patients hospitalised in intensive care unit indicated for transthoracic echocardiography examination

Exclusion Criteria:

• Age <18 years

• Insufficient imaging quality of transthoracic echocardiography

• Refusal of echocardiographic examination by patient

Related Conditions & MeSH terms

• Transthoracic Echocardiography

Intervention

Diagnostic Test:
• Transthoracic echocardiography
Conventional transthoracic echocardiographic examination at the intensive care unit.

Locations

Country	Name	City	State
Czechia	Masaryk Hospital Usti nad Labem	Usti nad Labem

Sponsors (2)

Lead Sponsor	Collaborator
Emergency Medical Service of the Central Bohemian Region, Czech Republic	Masaryk Hospital Usti nad Labem

Country where clinical trial is conducted

Czechia, 

References & Publications (1)

Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70. doi: 10.1093/ehjci/jev014. Review. Erratum in: Eur Heart J Cardiovasc Imaging. 2016 Apr;17(4):412. Eur Heart J Cardiovasc Imaging. 2016 Sep;17 (9):969. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Validity of sTAPSE in prediction of right ventricular systolic dysfunction	sTAPSE is a new potential echocardiographic parameter of right ventricular systolic function measurable from subcostal view.	During the intervention
Secondary	Correlation of sTAPSE with conventional TAPSE	sTAPSE is a new potential echocardiographic parameter of right ventricular systolic function measurable from subcostal view.	During the intervention