Transplantation Infection Clinical Trial
Official title:
The Induction Agent Effect on BK Viremia in Renal and Pancreas Transplant Patients
The increase immunosuppression in our transplant population has led to an unacceptable rate of patients at risk for BK virus nephropathy. Reducing induction immunosuppression by switching from Thymoglobulin to Simulect will reduce the incidence of serum positivity for BK by PCR.
Our standard of care has been changed from Thymoglobulin to Simulect and now patients were
enrolled in this observational trial to gather data on their outcomes related to BK viremia
and rejection rates. Two groups of patients were compared.
Retrospective (historical or control) group of subjects: patients who had received a kidney
transplant and were inducted with Thymoglobulin prior to study initiation.
Prospective group of subjects: patients who is scheduled to receive kidney transplant and
will be inducted with Simulect (Basiliximab).
Inductions in both groups was/is Standard of Care at a time of treatment.
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Observational Model: Case Control
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