Transplant;Failure,Kidney Clinical Trial
Official title:
Minimally Invasive Kidney Transplantation: Surgical Stress and Kidney Injury
This study aims to investigate the effect of robot-assisted laparoscopic kidney transplantation on kidney injury by measuring biomarkers of kidney injury which are found in blood and urine to establish if there is a significant difference between robotic and open surgery. The study will also investigate the potential benefits of minimally invasive surgery on the surgical trauma associated with open surgery by assessing the surgical stress response between groups of kidney transplant patients receiving either open or minimally invasive kidney transplants and by comparing wound healing with patients undergoing donor nephrectomy.
Status | Not yet recruiting |
Enrollment | 90 |
Est. completion date | December 2020 |
Est. primary completion date | December 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - patients over 18 years recieving a living donor kidney transplant at our institution Exclusion Criteria: - refuses consent |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Guy's and St Thomas' NHS Foundation Trust |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Expression of biomarkers of kidney injury | KIM-1, NGAL and Interleukin 18 will be measured pre-op and post operatively up to day 30. | 30 days post op | |
Secondary | Wound healing | Assessed by clinical markers such as infection and by ultrasound scan of incisions. | 3 time points post op up to 14 days. |
Status | Clinical Trial | Phase | |
---|---|---|---|
Withdrawn |
NCT05811468 -
Study Correlation Between Blood, Tissue Gene Expression, Donor Derived Cell Free DNA and Histopathology in Kidney Transplant Recipients
|
||
Active, not recruiting |
NCT04166149 -
Eliminating the Need for Pancreas Biopsy Using Peripheral Blood Cell-free DNA
|
||
Completed |
NCT03723668 -
Kidney Transplant Outcome and Organ Acceptance Practice Pattern: A Nationwide Analyses in the US and France
|
||
Recruiting |
NCT03737604 -
TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
|
Phase 4 | |
Completed |
NCT03765203 -
Utility of a Novel Dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
|
N/A | |
Completed |
NCT05809440 -
Effectiveness of 20m-MB in KTR Symptom Control
|
N/A | |
Enrolling by invitation |
NCT04491227 -
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection
|
||
Not yet recruiting |
NCT06396702 -
EASE-SOT Pilot Study
|
N/A | |
Recruiting |
NCT03310905 -
Abdominal Wall Transplant
|
N/A | |
Recruiting |
NCT05613010 -
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
|
N/A | |
Recruiting |
NCT06263257 -
The Effect of Mandala Therapy on Anxiety and Comfort in Kidney Transplant Recipients
|
N/A | |
Completed |
NCT04715412 -
Clinical Pharmacy Guided Patient Counselling and Adherence Support on Renal Transplant Recipients
|
N/A | |
Active, not recruiting |
NCT05449496 -
Dietary Intervention to Improve Kidney Transplant Outcomes
|
N/A | |
Not yet recruiting |
NCT06089473 -
Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates
|
N/A | |
Withdrawn |
NCT04473924 -
Standard Therapy or Individualized Immunosuppression For Lowering Adverse Event Risk
|
Phase 2 | |
Recruiting |
NCT04619732 -
Real-time Monitoring of Kidney Grafts on Hypothermic Machine Perfusion
|
N/A | |
Completed |
NCT03760263 -
Evaluation Dose Adjustments in Kidney Transplant Patients on Immediate Release and Extended Release Tacrolimus
|
Phase 4 | |
Active, not recruiting |
NCT03380962 -
Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT03436368 -
Continuous Spinal Anesthesia in Renal Transplantation
|
N/A | |
Recruiting |
NCT03778944 -
Enhancing Renal Graft Function During Donor Anesthesia
|
N/A |