Clinical Trials Logo
  1. Home
  2. Transfusion Related Complication
  3. NCT04413721
  4. Details
NCT04413721 Clinical Trial

Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver Transplantation

Transfusion Related Complication Clinical Trial

Official title:
Effects of Packed Red Blood Cell Storage Duration on Pediatric Living Donor Liver

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04413721
Other study ID # RBC20200505
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date July 1, 2020
Est. completion date August 1, 2024

Study information
Verified date May 2020
Source RenJi Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The patients assigned to either short-storage leukoreduced RBCs group (stored for ≤ 14 days) or longer-term storage leukoreduced RBCs group(stored for ≥21 days).When the hemoglobin concentration fell below 7.0 g per deciliter, PRBC were given to maintain the hemoglobin concentrations in the range of 7.0 to 10.0/dL. The primary outcome : Death from all causes in1-year after randomization. Secondary outcomes included: Intraoperative blood transfusion, Postoperative blood transfusion, Postoperative inflammatory reaction, Mechanical ventilation time in the intensive care unit, Lengths of stay in the intensive care unit and the hospital were also recorded.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 360
Est. completion date August 1, 2024
Est. primary completion date July 1, 2023
Accepts healthy volunteers No
Gender All
Age group 6 Months to 36 Months
Eligibility Inclusion Criteria:

- Our study included pediatric patients (6 months< the moon's age <36 months) who will receive standard living-donor liver transplantation (LDLT) in Renji Hospital.

Exclusion Criteria:

- The exclu¬sion criteria of the study were a congenital sufferer from heart, lung, kidney, nervous system or blood disease,active Lung infection,a history of liver transplantation,Multivisceral transplantation , refused to participate the study.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• RBC transfustion
When the hemoglobin concentration fell below 7.0 g per deciliter, RBC were given to maintain the hemoglobin concentrations in the range of 7.0 to 10.0g /dL

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
RenJi Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Mortality in in1-year after randomization Death from all causes in1-year after randomization. 1-year after randomization.
See also
  Status Clinical Trial Phase
Recruiting NCT05699005 - Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO Phase 1
Recruiting NCT06403163 - Transfusion Surveillance in Anaesthesia
Not yet recruiting NCT02587845 - Use of Transexamic Acid in Hip Replacement Phase 3
Completed NCT03365999 - Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement. Phase 2
Completed NCT03784794 - Patient Blood Management for Massive Obstetric Hemorrhage N/A
Not yet recruiting NCT02139995 - West-China Transfusion Score for Critically-ill Patients Phase 3
Completed NCT04513249 - Effects of Therapeutic Plasmaexhange on Viscoelastic Tests in Non-coagulopathic Patients
Not yet recruiting NCT03934112 - Impact of Transfusional Practice on the Morbidity and Mortality of Patients in Intensive Care Unit
Completed NCT03394274 - Restrictive Versus Liberal Transfusion, Major Surgeries N/A
Not yet recruiting NCT06399536 - Individualized ANH for Non-cardiac Surgery N/A
Withdrawn NCT04388722 - Monitoring Noninvasively for Infusion and Transfusion Optimization N/A
Completed NCT03476005 - Proficiency Based Training to Investigate WBIT N/A
Recruiting NCT03999229 - S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion Phase 1
Recruiting NCT02461264 - Transfusion Strategy in Hematological Intensive Care Unit Phase 3
Terminated NCT01915654 - Impact of RBC Transfusion Less Than 14 Days on Morbidity and Mortality in Cardiac Surgical Patients N/A
Not yet recruiting NCT05696210 - Evaluation of the 1-year Prognosis of Patients Under Veno-arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock With Blood Transfusion Requirement
Completed NCT04286984 - Implementation of a Patient Blood Management Program in Gastric Cancer Surgery
Completed NCT03764813 - Cord Blood Transfusion In Preterm Neonates (CB-TrIP)
Withdrawn NCT04383756 - Utilization of Donor Whole Blood for Blood Transfusion in Deceased Donor Liver Transplantation Early Phase 1
Completed NCT03815773 - PRospective Multicenter Observational Study on Transfusion Practice in Vv-ECMO Patients: The PROTECMO Study